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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRMT3 All Species: 24.85
Human Site: S59 Identified Species: 45.56
UniProt: O60678 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60678 NP_005779.1 531 59903 S59 F C N R L F T S A E E T F S H
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001092890 531 59784 S59 F C N R L F T S A E E T F S H
Dog Lupus familis XP_534089 541 60618 S69 F C H R L F I S A E E T F S H
Cat Felis silvestris
Mouse Mus musculus Q922H1 532 59884 S57 F C D R L F A S A E E T F S H
Rat Rattus norvegicus O70467 528 59401 S57 F C D R L F R S A E E T F S H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505718 571 63850 S99 F C D R V F T S A E E T F S H
Chicken Gallus gallus XP_420907 526 59430 S57 F C D R W F C S P E D V F C H
Frog Xenopus laevis Q8AV13 369 42306
Zebra Danio Brachydanio rerio Q5RGQ2 419 48204
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396035 525 60169 V58 S M A L E H L V A S H R F D L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001192186 519 58632 R60 S T V L T H C R E S H S F N L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O82210 366 41153
Baker's Yeast Sacchar. cerevisiae P38074 348 39768
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 94.1 90.9 N.A. 89.8 89.2 N.A. 78.8 70.8 35.4 35.7 N.A. N.A. 42.5 N.A. 45
Protein Similarity: 100 N.A. 96.8 95.1 N.A. 93.9 93.9 N.A. 85.9 83.2 49.1 52.3 N.A. N.A. 62.5 N.A. 63.6
P-Site Identity: 100 N.A. 100 86.6 N.A. 86.6 86.6 N.A. 86.6 53.3 0 0 N.A. N.A. 13.3 N.A. 6.6
P-Site Similarity: 100 N.A. 100 93.3 N.A. 93.3 93.3 N.A. 100 66.6 0 0 N.A. N.A. 13.3 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. 33.1 31.2 N.A.
Protein Similarity: N.A. N.A. N.A. 48.2 43.3 N.A.
P-Site Identity: N.A. N.A. N.A. 0 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 0 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 0 0 8 0 54 0 0 0 0 0 0 % A
% Cys: 0 54 0 0 0 0 16 0 0 0 0 0 0 8 0 % C
% Asp: 0 0 31 0 0 0 0 0 0 0 8 0 0 8 0 % D
% Glu: 0 0 0 0 8 0 0 0 8 54 47 0 0 0 0 % E
% Phe: 54 0 0 0 0 54 0 0 0 0 0 0 70 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 8 0 0 16 0 0 0 0 16 0 0 0 54 % H
% Ile: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 16 39 0 8 0 0 0 0 0 0 0 16 % L
% Met: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 16 0 0 0 0 0 0 0 0 0 0 8 0 % N
% Pro: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 54 0 0 8 8 0 0 0 8 0 0 0 % R
% Ser: 16 0 0 0 0 0 0 54 0 16 0 8 0 47 0 % S
% Thr: 0 8 0 0 8 0 24 0 0 0 0 47 0 0 0 % T
% Val: 0 0 8 0 8 0 0 8 0 0 0 8 0 0 0 % V
% Trp: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _