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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PEX10 All Species: 21.82
Human Site: S139 Identified Species: 36.92
UniProt: O60683 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60683 NP_002608.1 326 37069 S139 G P G G R G C S G A R R W M R
Chimpanzee Pan troglodytes XP_513729 326 36962 S139 G P G G R G C S G A R R W M R
Rhesus Macaque Macaca mulatta XP_001084130 326 37116 S139 V P G G R G C S G V R R W V R
Dog Lupus familis XP_546732 326 37150 S139 V L G G R G R S R A R H W V H
Cat Felis silvestris
Mouse Mus musculus B1AUE5 324 37139 S137 L P G G R S R S G A R R W V R
Rat Rattus norvegicus NP_001102875 324 37094 S137 L P G G R S R S G A R R W V R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517927 288 33368 W124 Q Q K K T L L W I V P L L R Q
Chicken Gallus gallus XP_417558 327 37834 T139 A L G L S S R T L I R N W I Q
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001005994 318 37293 F137 N P L S H M R F W I Q R A V G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_647624 299 34636 K133 T E I K P Q L K K I I Q R L R
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002308529 357 39556 S150 G T S V S V L S R L R Q K F N
Maize Zea mays NP_001142078 359 40033 A162 R F R G R V H A L W Q W V L Q
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SYU4 381 42596 S166 R M I D L P S S S Q V E T S T
Baker's Yeast Sacchar. cerevisiae Q05568 337 39080 L153 A A F C K G L L D F I L D V H
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.4 95 77.6 N.A. 82.8 84.3 N.A. 63.5 58 N.A. 52.7 N.A. 31.2 N.A. N.A. N.A.
Protein Similarity: 100 99.3 96.6 86.1 N.A. 88.3 88.9 N.A. 72.6 74.3 N.A. 69 N.A. 50 N.A. N.A. N.A.
P-Site Identity: 100 100 80 53.3 N.A. 73.3 73.3 N.A. 0 20 N.A. 13.3 N.A. 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 100 86.6 60 N.A. 80 80 N.A. 6.6 40 N.A. 26.6 N.A. 20 N.A. N.A. N.A.
Percent
Protein Identity: 28.5 27.8 N.A. 31.5 23.1 N.A.
Protein Similarity: 46.5 42 N.A. 45.9 41.8 N.A.
P-Site Identity: 20 13.3 N.A. 6.6 6.6 N.A.
P-Site Similarity: 26.6 40 N.A. 6.6 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 8 0 0 0 0 0 8 0 36 0 0 8 0 0 % A
% Cys: 0 0 0 8 0 0 22 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 8 0 0 0 0 8 0 0 0 8 0 0 % D
% Glu: 0 8 0 0 0 0 0 0 0 0 0 8 0 0 0 % E
% Phe: 0 8 8 0 0 0 0 8 0 8 0 0 0 8 0 % F
% Gly: 22 0 50 50 0 36 0 0 36 0 0 0 0 0 8 % G
% His: 0 0 0 0 8 0 8 0 0 0 0 8 0 0 15 % H
% Ile: 0 0 15 0 0 0 0 0 8 22 15 0 0 8 0 % I
% Lys: 0 0 8 15 8 0 0 8 8 0 0 0 8 0 0 % K
% Leu: 15 15 8 8 8 8 29 8 15 8 0 15 8 15 0 % L
% Met: 0 8 0 0 0 8 0 0 0 0 0 0 0 15 0 % M
% Asn: 8 0 0 0 0 0 0 0 0 0 0 8 0 0 8 % N
% Pro: 0 43 0 0 8 8 0 0 0 0 8 0 0 0 0 % P
% Gln: 8 8 0 0 0 8 0 0 0 8 15 15 0 0 22 % Q
% Arg: 15 0 8 0 50 0 36 0 15 0 58 43 8 8 43 % R
% Ser: 0 0 8 8 15 22 8 58 8 0 0 0 0 8 0 % S
% Thr: 8 8 0 0 8 0 0 8 0 0 0 0 8 0 8 % T
% Val: 15 0 0 8 0 15 0 0 0 15 8 0 8 43 0 % V
% Trp: 0 0 0 0 0 0 0 8 8 8 0 8 50 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _