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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PEX10 All Species: 26.36
Human Site: Y237 Identified Species: 44.62
UniProt: O60683 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60683 NP_002608.1 326 37069 Y237 L S M G L Q L Y G F R Q R Q R
Chimpanzee Pan troglodytes XP_513729 326 36962 Y237 L S V G L Q L Y G F R Q R Q R
Rhesus Macaque Macaca mulatta XP_001084130 326 37116 Y237 L S V G L Q L Y G F R Q R Q R
Dog Lupus familis XP_546732 326 37150 Y237 L S V G L Q L Y G F R Q R Q R
Cat Felis silvestris
Mouse Mus musculus B1AUE5 324 37139 Y235 L S M G L R L Y S F R Q K Q R
Rat Rattus norvegicus NP_001102875 324 37094 Y235 L S L G L Q L Y S F R Q K Q R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517927 288 33368 A207 G F R Q R R Q A R K E W K L H
Chicken Gallus gallus XP_417558 327 37834 Y237 L T I G V Q I Y S F Q Q K Q R
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001005994 318 37293 N231 I T L T L Q F N N L R Q R Q R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_647624 299 34636 R216 D A W R E H K R Q Q L E S I K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002308529 357 39556 L244 E G L R R S N L S S I A S S V
Maize Zea mays NP_001142078 359 40033 I248 E R L R R S N I S S I A S S I
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SYU4 381 42596 L271 E G L R R S N L S S I T S S I
Baker's Yeast Sacchar. cerevisiae Q05568 337 39080 V245 D S I T R S S V G L Q E R S E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.4 95 77.6 N.A. 82.8 84.3 N.A. 63.5 58 N.A. 52.7 N.A. 31.2 N.A. N.A. N.A.
Protein Similarity: 100 99.3 96.6 86.1 N.A. 88.3 88.9 N.A. 72.6 74.3 N.A. 69 N.A. 50 N.A. N.A. N.A.
P-Site Identity: 100 93.3 93.3 93.3 N.A. 80 80 N.A. 0 53.3 N.A. 46.6 N.A. 0 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. 13.3 93.3 N.A. 66.6 N.A. 20 N.A. N.A. N.A.
Percent
Protein Identity: 28.5 27.8 N.A. 31.5 23.1 N.A.
Protein Similarity: 46.5 42 N.A. 45.9 41.8 N.A.
P-Site Identity: 0 0 N.A. 0 20 N.A.
P-Site Similarity: 6.6 6.6 N.A. 6.6 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 0 0 0 8 0 0 0 15 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 15 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 22 0 0 0 8 0 0 0 0 0 8 15 0 0 8 % E
% Phe: 0 8 0 0 0 0 8 0 0 50 0 0 0 0 0 % F
% Gly: 8 15 0 50 0 0 0 0 36 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 8 % H
% Ile: 8 0 15 0 0 0 8 8 0 0 22 0 0 8 15 % I
% Lys: 0 0 0 0 0 0 8 0 0 8 0 0 29 0 8 % K
% Leu: 50 0 36 0 50 0 43 15 0 15 8 0 0 8 0 % L
% Met: 0 0 15 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 22 8 8 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 8 0 50 8 0 8 8 15 58 0 58 0 % Q
% Arg: 0 8 8 29 36 15 0 8 8 0 50 0 43 0 58 % R
% Ser: 0 50 0 0 0 29 8 0 43 22 0 0 29 29 0 % S
% Thr: 0 15 0 15 0 0 0 0 0 0 0 8 0 0 0 % T
% Val: 0 0 22 0 8 0 0 8 0 0 0 0 0 0 8 % V
% Trp: 0 0 8 0 0 0 0 0 0 0 0 8 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 50 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _