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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KPNA6 All Species: 54.55
Human Site: S109 Identified Species: 92.31
UniProt: O60684 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60684 NP_036448.1 536 60030 S109 Q K F R K L L S K E P S P P I
Chimpanzee Pan troglodytes XP_518711 559 63053 S132 Q K F R K L L S K E P N P P I
Rhesus Macaque Macaca mulatta XP_001102290 566 62946 S139 Q K F R K L L S K E P S P P I
Dog Lupus familis XP_864794 536 59912 S109 Q K F R K L L S K E P S P P I
Cat Felis silvestris
Mouse Mus musculus O35345 536 59946 S109 Q K F R K L L S K E P S P P I
Rat Rattus norvegicus Q56R16 536 60281 S109 Q K F R K L L S K E P N P P I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506386 535 59550 S106 Q K F R K L L S K E P N P P I
Chicken Gallus gallus Q5ZML1 538 60176 S111 Q K F R K L L S K E P N P P I
Frog Xenopus laevis P52170 522 57670 S102 Q A A R K M L S R E R N P P L
Zebra Danio Brachydanio rerio Q503E9 536 59774 S109 Q K F R K L L S K E P N P P I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P52295 522 57803 S98 Q S A R K M L S R E R N P P I
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q19969 514 56144 S94 Q Q A R K M L S T D R N P P I
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q96321 532 58626 S101 T Q F R K L L S I E R S P P I
Baker's Yeast Sacchar. cerevisiae Q02821 542 60423 S116 V K F R Q I L S R E H R P P I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 81 94.6 99.8 N.A. 99.2 82 N.A. 94.4 81.2 44.9 83.2 N.A. 47.5 N.A. 42.9 N.A.
Protein Similarity: 100 87.6 94.6 99.8 N.A. 99.4 88.9 N.A. 97 90.1 62.8 91.2 N.A. 63.8 N.A. 60.6 N.A.
P-Site Identity: 100 93.3 100 100 N.A. 100 93.3 N.A. 93.3 93.3 53.3 93.3 N.A. 60 N.A. 53.3 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 80 100 N.A. 80 N.A. 80 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 55.4 50.5 N.A.
Protein Similarity: N.A. N.A. N.A. 69.7 68.2 N.A.
P-Site Identity: N.A. N.A. N.A. 73.3 60 N.A.
P-Site Similarity: N.A. N.A. N.A. 80 80 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 22 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 93 0 0 0 0 0 % E
% Phe: 0 0 79 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % H
% Ile: 0 0 0 0 0 8 0 0 8 0 0 0 0 0 93 % I
% Lys: 0 72 0 0 93 0 0 0 65 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 72 100 0 0 0 0 0 0 0 8 % L
% Met: 0 0 0 0 0 22 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 58 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 65 0 100 100 0 % P
% Gln: 86 15 0 0 8 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 100 0 0 0 0 22 0 29 8 0 0 0 % R
% Ser: 0 8 0 0 0 0 0 100 0 0 0 36 0 0 0 % S
% Thr: 8 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % T
% Val: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _