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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KPNA6
All Species:
47.58
Human Site:
Y501
Identified Species:
80.51
UniProt:
O60684
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60684
NP_036448.1
536
60030
Y501
A
F
D
L
I
E
H
Y
F
G
V
E
D
D
D
Chimpanzee
Pan troglodytes
XP_518711
559
63053
Y524
A
F
D
L
I
E
H
Y
F
G
V
E
E
D
D
Rhesus Macaque
Macaca mulatta
XP_001102290
566
62946
Y531
A
F
D
L
I
E
H
Y
F
G
V
E
D
D
D
Dog
Lupus familis
XP_864794
536
59912
Y501
A
F
D
L
I
E
H
Y
F
G
V
E
D
D
D
Cat
Felis silvestris
Mouse
Mus musculus
O35345
536
59946
Y501
A
F
D
L
I
E
H
Y
F
G
V
E
D
D
D
Rat
Rattus norvegicus
Q56R16
536
60281
Y501
A
F
D
L
I
E
R
Y
F
G
V
E
E
D
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506386
535
59550
Y498
A
F
D
L
I
E
H
Y
F
G
V
E
D
D
A
Chicken
Gallus gallus
Q5ZML1
538
60176
Y503
A
F
D
L
I
E
H
Y
F
G
T
E
D
E
D
Frog
Xenopus laevis
P52170
522
57670
Y488
A
L
A
L
I
E
K
Y
F
S
G
E
E
A
D
Zebra Danio
Brachydanio rerio
Q503E9
536
59774
Y501
A
F
D
L
I
E
H
Y
F
G
V
E
E
E
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P52295
522
57803
Y485
A
Y
A
I
I
D
T
Y
F
S
N
G
D
D
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19969
514
56144
F477
A
F
E
I
I
D
N
F
F
S
S
D
D
E
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q96321
532
58626
Y493
A
V
K
I
L
E
T
Y
W
L
E
E
E
D
D
Baker's Yeast
Sacchar. cerevisiae
Q02821
542
60423
Y508
A
Y
K
I
I
E
T
Y
F
G
E
E
E
D
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81
94.6
99.8
N.A.
99.2
82
N.A.
94.4
81.2
44.9
83.2
N.A.
47.5
N.A.
42.9
N.A.
Protein Similarity:
100
87.6
94.6
99.8
N.A.
99.4
88.9
N.A.
97
90.1
62.8
91.2
N.A.
63.8
N.A.
60.6
N.A.
P-Site Identity:
100
93.3
100
100
N.A.
100
86.6
N.A.
93.3
86.6
53.3
86.6
N.A.
40
N.A.
33.3
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
93.3
N.A.
93.3
93.3
60
100
N.A.
66.6
N.A.
80
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
55.4
50.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
69.7
68.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
53.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
100
0
15
0
0
0
0
0
0
0
0
0
0
8
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
65
0
0
15
0
0
0
0
0
8
58
72
72
% D
% Glu:
0
0
8
0
0
86
0
0
0
0
15
86
43
22
8
% E
% Phe:
0
72
0
0
0
0
0
8
93
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
72
8
8
0
0
0
% G
% His:
0
0
0
0
0
0
58
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
29
93
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
15
0
0
0
8
0
0
0
0
0
0
0
0
% K
% Leu:
0
8
0
72
8
0
0
0
0
8
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
8
0
0
0
8
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
22
8
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
22
0
0
0
8
0
0
0
8
% T
% Val:
0
8
0
0
0
0
0
0
0
0
58
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
0
15
0
0
0
0
0
93
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _