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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TPST2
All Species:
44.24
Human Site:
S116
Identified Species:
88.48
UniProt:
O60704
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60704
NP_001008566.1
377
41912
S116
M
R
Q
A
W
S
K
S
G
R
E
K
L
R
L
Chimpanzee
Pan troglodytes
XP_001172350
377
41866
S116
M
R
Q
A
W
S
K
S
G
R
E
K
L
R
L
Rhesus Macaque
Macaca mulatta
XP_001105516
632
69858
S327
M
R
Q
A
W
S
K
S
G
R
E
K
L
R
L
Dog
Lupus familis
XP_543458
446
49420
S185
M
R
Q
A
W
S
K
S
G
R
E
K
L
R
L
Cat
Felis silvestris
Mouse
Mus musculus
O88856
376
42049
S115
M
R
Q
A
W
T
K
S
G
R
E
K
L
R
L
Rat
Rattus norvegicus
Q5RJS8
376
42050
S115
M
R
Q
A
W
T
K
S
G
R
E
K
L
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZJI0
371
42023
S114
M
R
Q
A
W
S
K
S
G
R
E
K
M
R
L
Frog
Xenopus laevis
NP_001088427
375
42345
S118
M
R
Q
A
W
S
K
S
G
S
E
K
M
R
L
Zebra Danio
Brachydanio rerio
Q9PTE6
355
40179
S114
M
K
Q
M
W
S
R
S
G
R
E
K
M
R
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VYB7
499
58032
S118
L
R
S
H
W
L
K
S
E
K
E
S
L
R
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O77081
380
43295
S117
L
R
S
Q
W
K
K
S
E
K
E
W
N
R
L
Sea Urchin
Strong. purpuratus
XP_001190618
798
90248
S107
M
R
A
Q
W
I
R
S
S
K
E
H
A
R
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
56.9
80
N.A.
94.4
93.9
N.A.
N.A.
81.9
73.4
63.1
N.A.
44.8
N.A.
52.1
29
Protein Similarity:
100
100
58
82.2
N.A.
96.8
96.5
N.A.
N.A.
90.7
89.1
76.1
N.A.
56.1
N.A.
67.8
36.7
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
N.A.
93.3
86.6
73.3
N.A.
53.3
N.A.
46.6
46.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
93.3
93.3
N.A.
66.6
N.A.
60
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
67
0
0
0
0
0
0
0
0
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
17
0
100
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
75
0
0
0
0
0
0
% G
% His:
0
0
0
9
0
0
0
0
0
0
0
9
0
0
0
% H
% Ile:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
9
0
0
0
9
84
0
0
25
0
75
0
0
0
% K
% Leu:
17
0
0
0
0
9
0
0
0
0
0
0
59
0
100
% L
% Met:
84
0
0
9
0
0
0
0
0
0
0
0
25
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
75
17
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
92
0
0
0
0
17
0
0
67
0
0
0
100
0
% R
% Ser:
0
0
17
0
0
59
0
100
9
9
0
9
0
0
0
% S
% Thr:
0
0
0
0
0
17
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
100
0
0
0
0
0
0
9
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _