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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TPST2
All Species:
17.53
Human Site:
S371
Identified Species:
35.06
UniProt:
O60704
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60704
NP_001008566.1
377
41912
S371
Q
V
N
Q
N
S
T
S
S
H
L
G
S
S
_
Chimpanzee
Pan troglodytes
XP_001172350
377
41866
S371
Q
V
N
Q
S
S
T
S
S
H
L
G
S
S
_
Rhesus Macaque
Macaca mulatta
XP_001105516
632
69858
Q582
F
L
Q
M
W
K
L
Q
P
P
E
E
M
F
S
Dog
Lupus familis
XP_543458
446
49420
S440
Q
V
N
Q
N
S
T
S
S
H
L
G
S
S
_
Cat
Felis silvestris
Mouse
Mus musculus
O88856
376
42049
S370
Q
V
N
Q
N
S
T
S
P
H
L
G
S
S
_
Rat
Rattus norvegicus
Q5RJS8
376
42050
S370
Q
V
N
Q
N
S
T
S
P
H
L
G
S
S
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZJI0
371
42023
V363
N
L
K
G
H
L
Q
V
T
Q
N
T
S
S
S
Frog
Xenopus laevis
NP_001088427
375
42345
K366
S
N
L
K
G
Y
A
K
V
H
Q
S
N
S
S
Zebra Danio
Brachydanio rerio
Q9PTE6
355
40179
R343
P
L
V
L
D
N
T
R
R
L
Q
K
S
P
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VYB7
499
58032
D373
Q
M
S
S
S
E
D
D
N
T
N
T
I
I
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O77081
380
43295
K370
N
D
P
G
R
V
D
K
P
I
V
D
N
E
V
Sea Urchin
Strong. purpuratus
XP_001190618
798
90248
Q362
R
E
K
D
I
D
Q
Q
I
E
G
P
R
D
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
56.9
80
N.A.
94.4
93.9
N.A.
N.A.
81.9
73.4
63.1
N.A.
44.8
N.A.
52.1
29
Protein Similarity:
100
100
58
82.2
N.A.
96.8
96.5
N.A.
N.A.
90.7
89.1
76.1
N.A.
56.1
N.A.
67.8
36.7
P-Site Identity:
100
92.8
0
100
N.A.
92.8
92.8
N.A.
N.A.
13.3
13.3
13.3
N.A.
6.6
N.A.
0
0
P-Site Similarity:
100
100
6.6
100
N.A.
92.8
92.8
N.A.
N.A.
33.3
26.6
33.3
N.A.
33.3
N.A.
13.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
9
9
9
17
9
0
0
0
9
0
9
0
% D
% Glu:
0
9
0
0
0
9
0
0
0
9
9
9
0
9
9
% E
% Phe:
9
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% F
% Gly:
0
0
0
17
9
0
0
0
0
0
9
42
0
0
0
% G
% His:
0
0
0
0
9
0
0
0
0
50
0
0
0
0
0
% H
% Ile:
0
0
0
0
9
0
0
0
9
9
0
0
9
9
0
% I
% Lys:
0
0
17
9
0
9
0
17
0
0
0
9
0
0
0
% K
% Leu:
0
25
9
9
0
9
9
0
0
9
42
0
0
0
0
% L
% Met:
0
9
0
9
0
0
0
0
0
0
0
0
9
0
0
% M
% Asn:
17
9
42
0
34
9
0
0
9
0
17
0
17
0
9
% N
% Pro:
9
0
9
0
0
0
0
0
34
9
0
9
0
9
9
% P
% Gln:
50
0
9
42
0
0
17
17
0
9
17
0
0
0
0
% Q
% Arg:
9
0
0
0
9
0
0
9
9
0
0
0
9
0
0
% R
% Ser:
9
0
9
9
17
42
0
42
25
0
0
9
59
59
25
% S
% Thr:
0
0
0
0
0
0
50
0
9
9
0
17
0
0
0
% T
% Val:
0
42
9
0
0
9
0
9
9
0
9
0
0
0
9
% V
% Trp:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
42
% _