Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TPST2 All Species: 20.3
Human Site: S40 Identified Species: 40.61
UniProt: O60704 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60704 NP_001008566.1 377 41912 S40 A V L A G L R S P R G A M R P
Chimpanzee Pan troglodytes XP_001172350 377 41866 S40 A V L A G L R S P R G A M R P
Rhesus Macaque Macaca mulatta XP_001105516 632 69858 S251 A V L A G L R S P R G A M R P
Dog Lupus familis XP_543458 446 49420 S109 A A L G G P R S P R R A M R P
Cat Felis silvestris
Mouse Mus musculus O88856 376 42049 N40 A V L G G T R N P R R M R P E
Rat Rattus norvegicus Q5RJS8 376 42050 S40 A V L G G V R S P R R M Q P E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZJI0 371 42023 T21 S V V A L M V T L H L G Q Q V
Frog Xenopus laevis NP_001088427 375 42345 R42 L D G S Y G K R N R G V M K P
Zebra Danio Brachydanio rerio Q9PTE6 355 40179 L24 S S V T V F Y L C R H A M D C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VYB7 499 58032 F26 I V I T M F L F K F T E L R P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O77081 380 43295 T23 F I L F Y F I T A R T A D D P
Sea Urchin Strong. purpuratus XP_001190618 798 90248 T32 H S N C G D T T E N V R M V P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 56.9 80 N.A. 94.4 93.9 N.A. N.A. 81.9 73.4 63.1 N.A. 44.8 N.A. 52.1 29
Protein Similarity: 100 100 58 82.2 N.A. 96.8 96.5 N.A. N.A. 90.7 89.1 76.1 N.A. 56.1 N.A. 67.8 36.7
P-Site Identity: 100 100 100 73.3 N.A. 46.6 53.3 N.A. N.A. 13.3 26.6 20 N.A. 20 N.A. 26.6 20
P-Site Similarity: 100 100 100 73.3 N.A. 53.3 60 N.A. N.A. 46.6 46.6 33.3 N.A. 33.3 N.A. 40 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 50 9 0 34 0 0 0 0 9 0 0 50 0 0 0 % A
% Cys: 0 0 0 9 0 0 0 0 9 0 0 0 0 0 9 % C
% Asp: 0 9 0 0 0 9 0 0 0 0 0 0 9 17 0 % D
% Glu: 0 0 0 0 0 0 0 0 9 0 0 9 0 0 17 % E
% Phe: 9 0 0 9 0 25 0 9 0 9 0 0 0 0 0 % F
% Gly: 0 0 9 25 59 9 0 0 0 0 34 9 0 0 0 % G
% His: 9 0 0 0 0 0 0 0 0 9 9 0 0 0 0 % H
% Ile: 9 9 9 0 0 0 9 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 9 0 9 0 0 0 0 9 0 % K
% Leu: 9 0 59 0 9 25 9 9 9 0 9 0 9 0 0 % L
% Met: 0 0 0 0 9 9 0 0 0 0 0 17 59 0 0 % M
% Asn: 0 0 9 0 0 0 0 9 9 9 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 9 0 0 50 0 0 0 0 17 67 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 17 9 0 % Q
% Arg: 0 0 0 0 0 0 50 9 0 75 25 9 9 42 0 % R
% Ser: 17 17 0 9 0 0 0 42 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 17 0 9 9 25 0 0 17 0 0 0 0 % T
% Val: 0 59 17 0 9 9 9 0 0 0 9 9 0 9 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 17 0 9 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _