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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TPST2
All Species:
36.67
Human Site:
T212
Identified Species:
73.33
UniProt:
O60704
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60704
NP_001008566.1
377
41912
T212
S
S
Y
R
D
C
L
T
K
W
N
K
A
I
E
Chimpanzee
Pan troglodytes
XP_001172350
377
41866
T212
S
S
Y
R
D
C
L
T
K
W
N
K
A
I
E
Rhesus Macaque
Macaca mulatta
XP_001105516
632
69858
T423
S
S
Y
R
D
C
L
T
K
W
N
K
A
I
E
Dog
Lupus familis
XP_543458
446
49420
T281
S
S
Y
R
D
C
L
T
K
W
N
K
A
I
E
Cat
Felis silvestris
Mouse
Mus musculus
O88856
376
42049
T211
S
S
Y
R
D
C
L
T
K
W
N
K
A
I
E
Rat
Rattus norvegicus
Q5RJS8
376
42050
T211
S
S
Y
R
D
C
L
T
K
W
N
K
A
I
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZJI0
371
42023
T210
N
C
Y
R
D
C
L
T
K
W
N
K
A
I
E
Frog
Xenopus laevis
NP_001088427
375
42345
T214
N
S
Y
R
D
C
L
T
K
W
N
K
A
V
E
Zebra Danio
Brachydanio rerio
Q9PTE6
355
40179
S192
A
S
V
H
S
M
I
S
R
K
V
T
I
A
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VYB7
499
58032
Q214
S
S
Y
R
Q
C
M
Q
K
W
N
H
A
I
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O77081
380
43295
T213
N
D
F
R
Q
C
M
T
K
W
N
A
A
I
Q
Sea Urchin
Strong. purpuratus
XP_001190618
798
90248
K203
T
N
Y
R
D
C
L
K
K
W
N
Q
A
V
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
56.9
80
N.A.
94.4
93.9
N.A.
N.A.
81.9
73.4
63.1
N.A.
44.8
N.A.
52.1
29
Protein Similarity:
100
100
58
82.2
N.A.
96.8
96.5
N.A.
N.A.
90.7
89.1
76.1
N.A.
56.1
N.A.
67.8
36.7
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
86.6
86.6
6.6
N.A.
73.3
N.A.
53.3
66.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
93.3
100
33.3
N.A.
80
N.A.
80
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
0
0
0
0
0
0
0
9
92
9
0
% A
% Cys:
0
9
0
0
0
92
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
0
75
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
84
% E
% Phe:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% G
% His:
0
0
0
9
0
0
0
0
0
0
0
9
0
0
0
% H
% Ile:
0
0
0
0
0
0
9
0
0
0
0
0
9
75
0
% I
% Lys:
0
0
0
0
0
0
0
9
92
9
0
67
0
0
0
% K
% Leu:
0
0
0
0
0
0
75
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
9
17
0
0
0
0
0
0
0
0
% M
% Asn:
25
9
0
0
0
0
0
0
0
0
92
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
17
0
0
9
0
0
0
9
0
0
9
% Q
% Arg:
0
0
0
92
0
0
0
0
9
0
0
0
0
0
0
% R
% Ser:
59
75
0
0
9
0
0
9
0
0
0
0
0
0
0
% S
% Thr:
9
0
0
0
0
0
0
75
0
0
0
9
0
0
0
% T
% Val:
0
0
9
0
0
0
0
0
0
0
9
0
0
17
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
92
0
0
0
0
0
% W
% Tyr:
0
0
84
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _