KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TPST2
All Species:
44.55
Human Site:
T286
Identified Species:
89.09
UniProt:
O60704
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60704
NP_001008566.1
377
41912
T286
L
S
K
I
E
R
S
T
D
Q
V
I
K
P
V
Chimpanzee
Pan troglodytes
XP_001172350
377
41866
T286
L
S
K
I
E
R
S
T
D
Q
V
I
K
P
V
Rhesus Macaque
Macaca mulatta
XP_001105516
632
69858
T497
L
S
K
I
E
R
S
T
D
Q
V
I
K
P
V
Dog
Lupus familis
XP_543458
446
49420
T355
L
S
K
I
E
R
S
T
D
Q
V
I
K
P
V
Cat
Felis silvestris
Mouse
Mus musculus
O88856
376
42049
T285
L
S
K
I
E
R
S
T
D
Q
V
I
K
P
V
Rat
Rattus norvegicus
Q5RJS8
376
42050
T285
L
S
K
I
E
R
S
T
D
Q
V
I
K
P
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZJI0
371
42023
T284
L
S
K
I
E
R
S
T
D
Q
V
I
K
P
V
Frog
Xenopus laevis
NP_001088427
375
42345
T288
L
S
K
T
E
K
S
T
D
Q
V
M
K
P
V
Zebra Danio
Brachydanio rerio
Q9PTE6
355
40179
H264
W
N
D
A
V
L
H
H
E
E
L
I
G
K
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VYB7
499
58032
S288
L
S
K
V
E
R
S
S
D
Q
V
I
K
P
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O77081
380
43295
S285
L
S
N
V
E
R
S
S
D
Q
V
V
K
P
V
Sea Urchin
Strong. purpuratus
XP_001190618
798
90248
T277
L
S
R
K
E
K
S
T
D
Q
V
I
K
P
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
56.9
80
N.A.
94.4
93.9
N.A.
N.A.
81.9
73.4
63.1
N.A.
44.8
N.A.
52.1
29
Protein Similarity:
100
100
58
82.2
N.A.
96.8
96.5
N.A.
N.A.
90.7
89.1
76.1
N.A.
56.1
N.A.
67.8
36.7
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
80
6.6
N.A.
86.6
N.A.
73.3
80
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
93.3
33.3
N.A.
100
N.A.
93.3
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
0
0
0
0
0
92
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
92
0
0
0
9
9
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% G
% His:
0
0
0
0
0
0
9
9
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
59
0
0
0
0
0
0
0
84
0
0
0
% I
% Lys:
0
0
75
9
0
17
0
0
0
0
0
0
92
9
0
% K
% Leu:
92
0
0
0
0
9
0
0
0
0
9
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% M
% Asn:
0
9
9
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
92
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
92
0
0
0
0
0
% Q
% Arg:
0
0
9
0
0
75
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
92
0
0
0
0
92
17
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
9
0
0
0
75
0
0
0
0
0
0
0
% T
% Val:
0
0
0
17
9
0
0
0
0
0
92
9
0
0
92
% V
% Trp:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _