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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TPST2 All Species: 18.18
Human Site: T355 Identified Species: 36.36
UniProt: O60704 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60704 NP_001008566.1 377 41912 T355 V L K G D Y K T P A N L K G Y
Chimpanzee Pan troglodytes XP_001172350 377 41866 T355 V L K G D Y K T P A N L K G Y
Rhesus Macaque Macaca mulatta XP_001105516 632 69858 R566 V S V H L Y L R K C A L G D L
Dog Lupus familis XP_543458 446 49420 T424 V L K G D Y K T P A N L K G Y
Cat Felis silvestris
Mouse Mus musculus O88856 376 42049 T354 V L K G D Y K T P A N L K G Y
Rat Rattus norvegicus Q5RJS8 376 42050 T354 V L K G D Y K T P A N L K G Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZJI0 371 42023 L347 V N N T H R V L K G D Y K T P
Frog Xenopus laevis NP_001088427 375 42345 V350 V L N N T H R V M K G D F K T
Zebra Danio Brachydanio rerio Q9PTE6 355 40179 N327 L G Y D P H A N P P N Y G R P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VYB7 499 58032 W357 L K A N R M L W E S K A K Q V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O77081 380 43295 W354 V H K N G A E W Y K K A V Q V
Sea Urchin Strong. purpuratus XP_001190618 798 90248 F346 I A D N A A G F N E N L K R V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 56.9 80 N.A. 94.4 93.9 N.A. N.A. 81.9 73.4 63.1 N.A. 44.8 N.A. 52.1 29
Protein Similarity: 100 100 58 82.2 N.A. 96.8 96.5 N.A. N.A. 90.7 89.1 76.1 N.A. 56.1 N.A. 67.8 36.7
P-Site Identity: 100 100 20 100 N.A. 100 100 N.A. N.A. 13.3 13.3 13.3 N.A. 6.6 N.A. 13.3 20
P-Site Similarity: 100 100 20 100 N.A. 100 100 N.A. N.A. 20 26.6 26.6 N.A. 20 N.A. 20 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 9 0 9 17 9 0 0 42 9 17 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % C
% Asp: 0 0 9 9 42 0 0 0 0 0 9 9 0 9 0 % D
% Glu: 0 0 0 0 0 0 9 0 9 9 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 9 0 0 0 0 9 0 0 % F
% Gly: 0 9 0 42 9 0 9 0 0 9 9 0 17 42 0 % G
% His: 0 9 0 9 9 17 0 0 0 0 0 0 0 0 0 % H
% Ile: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 9 50 0 0 0 42 0 17 17 17 0 67 9 0 % K
% Leu: 17 50 0 0 9 0 17 9 0 0 0 59 0 0 9 % L
% Met: 0 0 0 0 0 9 0 0 9 0 0 0 0 0 0 % M
% Asn: 0 9 17 34 0 0 0 9 9 0 59 0 0 0 0 % N
% Pro: 0 0 0 0 9 0 0 0 50 9 0 0 0 0 17 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 17 0 % Q
% Arg: 0 0 0 0 9 9 9 9 0 0 0 0 0 17 0 % R
% Ser: 0 9 0 0 0 0 0 0 0 9 0 0 0 0 0 % S
% Thr: 0 0 0 9 9 0 0 42 0 0 0 0 0 9 9 % T
% Val: 75 0 9 0 0 0 9 9 0 0 0 0 9 0 25 % V
% Trp: 0 0 0 0 0 0 0 17 0 0 0 0 0 0 0 % W
% Tyr: 0 0 9 0 0 50 0 0 9 0 0 17 0 0 42 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _