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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TPST2
All Species:
18.79
Human Site:
Y353
Identified Species:
37.58
UniProt:
O60704
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60704
NP_001008566.1
377
41912
Y353
Q
R
V
L
K
G
D
Y
K
T
P
A
N
L
K
Chimpanzee
Pan troglodytes
XP_001172350
377
41866
Y353
Q
R
V
L
K
G
D
Y
K
T
P
A
N
L
K
Rhesus Macaque
Macaca mulatta
XP_001105516
632
69858
Y564
Q
R
V
S
V
H
L
Y
L
R
K
C
A
L
G
Dog
Lupus familis
XP_543458
446
49420
Y422
H
R
V
L
K
G
D
Y
K
T
P
A
N
L
K
Cat
Felis silvestris
Mouse
Mus musculus
O88856
376
42049
Y352
H
R
V
L
K
G
D
Y
K
T
P
A
N
L
K
Rat
Rattus norvegicus
Q5RJS8
376
42050
Y352
H
R
V
L
K
G
D
Y
K
T
P
A
N
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZJI0
371
42023
R345
L
V
V
N
N
T
H
R
V
L
K
G
D
Y
K
Frog
Xenopus laevis
NP_001088427
375
42345
H348
A
M
V
L
N
N
T
H
R
V
M
K
G
D
F
Zebra Danio
Brachydanio rerio
Q9PTE6
355
40179
H325
A
R
L
G
Y
D
P
H
A
N
P
P
N
Y
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VYB7
499
58032
M355
S
K
L
K
A
N
R
M
L
W
E
S
K
A
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O77081
380
43295
A352
E
D
V
H
K
N
G
A
E
W
Y
K
K
A
V
Sea Urchin
Strong. purpuratus
XP_001190618
798
90248
A344
Q
K
I
A
D
N
A
A
G
F
N
E
N
L
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
56.9
80
N.A.
94.4
93.9
N.A.
N.A.
81.9
73.4
63.1
N.A.
44.8
N.A.
52.1
29
Protein Similarity:
100
100
58
82.2
N.A.
96.8
96.5
N.A.
N.A.
90.7
89.1
76.1
N.A.
56.1
N.A.
67.8
36.7
P-Site Identity:
100
100
33.3
93.3
N.A.
93.3
93.3
N.A.
N.A.
13.3
13.3
20
N.A.
6.6
N.A.
13.3
26.6
P-Site Similarity:
100
100
33.3
93.3
N.A.
93.3
93.3
N.A.
N.A.
20
26.6
33.3
N.A.
26.6
N.A.
26.6
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
0
0
9
9
0
9
17
9
0
0
42
9
17
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% C
% Asp:
0
9
0
0
9
9
42
0
0
0
0
0
9
9
0
% D
% Glu:
9
0
0
0
0
0
0
0
9
0
9
9
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
9
% F
% Gly:
0
0
0
9
0
42
9
0
9
0
0
9
9
0
17
% G
% His:
25
0
0
9
0
9
9
17
0
0
0
0
0
0
0
% H
% Ile:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
17
0
9
50
0
0
0
42
0
17
17
17
0
67
% K
% Leu:
9
0
17
50
0
0
9
0
17
9
0
0
0
59
0
% L
% Met:
0
9
0
0
0
0
0
9
0
0
9
0
0
0
0
% M
% Asn:
0
0
0
9
17
34
0
0
0
9
9
0
59
0
0
% N
% Pro:
0
0
0
0
0
0
9
0
0
0
50
9
0
0
0
% P
% Gln:
34
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
59
0
0
0
0
9
9
9
9
0
0
0
0
0
% R
% Ser:
9
0
0
9
0
0
0
0
0
0
0
9
0
0
0
% S
% Thr:
0
0
0
0
0
9
9
0
0
42
0
0
0
0
0
% T
% Val:
0
9
75
0
9
0
0
0
9
9
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
17
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
0
0
50
0
0
9
0
0
17
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _