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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC24A1
All Species:
4.55
Human Site:
S378
Identified Species:
10
UniProt:
O60721
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60721
NP_004718.1
1099
121374
S378
P
S
T
A
P
S
T
S
T
T
P
T
V
R
A
Chimpanzee
Pan troglodytes
XP_001174585
1096
121151
S378
P
S
T
A
P
S
T
S
T
T
P
T
V
R
A
Rhesus Macaque
Macaca mulatta
XP_001103481
812
89131
K175
P
T
P
T
G
E
M
K
S
Y
S
P
T
Q
V
Dog
Lupus familis
XP_864917
651
72717
K14
T
A
I
T
F
L
E
K
W
C
L
D
K
S
L
Cat
Felis silvestris
Mouse
Mus musculus
Q99PD7
645
71896
D8
M
P
P
P
G
D
Q
D
C
A
R
R
R
S
R
Rat
Rattus norvegicus
Q9QZM6
1181
129963
M378
P
M
T
P
S
P
S
M
T
A
I
L
F
P
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514353
346
38802
Chicken
Gallus gallus
Q9IAL8
663
73753
V26
A
V
V
S
L
L
S
V
Y
Q
L
Q
F
S
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q49SH1
513
56764
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9U6A0
888
95868
Q251
G
G
V
G
A
P
S
Q
T
S
G
E
D
E
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787540
651
70927
W14
Y
M
C
S
R
T
R
W
A
R
V
L
C
L
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
69.1
39.4
N.A.
26.4
67.2
N.A.
21.2
42.9
N.A.
20
N.A.
32.6
N.A.
N.A.
30.1
Protein Similarity:
100
99.2
71
47.5
N.A.
38.6
74.9
N.A.
26.6
51
N.A.
32
N.A.
47.9
N.A.
N.A.
39.6
P-Site Identity:
100
100
6.6
0
N.A.
0
20
N.A.
0
0
N.A.
0
N.A.
13.3
N.A.
N.A.
0
P-Site Similarity:
100
100
26.6
6.6
N.A.
0
26.6
N.A.
0
13.3
N.A.
0
N.A.
26.6
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
19
10
0
0
0
10
19
0
0
0
0
28
% A
% Cys:
0
0
10
0
0
0
0
0
10
10
0
0
10
0
10
% C
% Asp:
0
0
0
0
0
10
0
10
0
0
0
10
10
0
0
% D
% Glu:
0
0
0
0
0
10
10
0
0
0
0
10
0
10
10
% E
% Phe:
0
0
0
0
10
0
0
0
0
0
0
0
19
0
0
% F
% Gly:
10
10
0
10
19
0
0
0
0
0
10
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
0
0
0
0
10
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
19
0
0
0
0
10
0
0
% K
% Leu:
0
0
0
0
10
19
0
0
0
0
19
19
0
10
10
% L
% Met:
10
19
0
0
0
0
10
10
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
37
10
19
19
19
19
0
0
0
0
19
10
0
10
10
% P
% Gln:
0
0
0
0
0
0
10
10
0
10
0
10
0
10
0
% Q
% Arg:
0
0
0
0
10
0
10
0
0
10
10
10
10
19
10
% R
% Ser:
0
19
0
19
10
19
28
19
10
10
10
0
0
28
0
% S
% Thr:
10
10
28
19
0
10
19
0
37
19
0
19
10
0
0
% T
% Val:
0
10
19
0
0
0
0
10
0
0
10
0
19
0
10
% V
% Trp:
0
0
0
0
0
0
0
10
10
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
10
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _