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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC24A1 All Species: 6.97
Human Site: S657 Identified Species: 15.33
UniProt: O60721 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60721 NP_004718.1 1099 121374 S657 P S L L T R G S S S T S L H N
Chimpanzee Pan troglodytes XP_001174585 1096 121151 S657 P S L L T R G S S S T S L H N
Rhesus Macaque Macaca mulatta XP_001103481 812 89131 D443 P K G E Y P P D L F S V E E R
Dog Lupus familis XP_864917 651 72717 F282 G Y V V F M K F N V Q V E R W
Cat Felis silvestris
Mouse Mus musculus Q99PD7 645 71896 N276 K G A G N M V N G L A N N A E
Rat Rattus norvegicus Q9QZM6 1181 129963 A694 P A V T V T P A P A P E D K G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514353 346 38802
Chicken Gallus gallus Q9IAL8 663 73753 L294 K E E L S K K L N A V Q A A S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q49SH1 513 56764 V144 T A F L G V F V T K G D I G V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9U6A0 888 95868 S519 A A N S S E T S M A T Q P G G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_787540 651 70927 S282 Q P H E Q S A S R P E S A R S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 69.1 39.4 N.A. 26.4 67.2 N.A. 21.2 42.9 N.A. 20 N.A. 32.6 N.A. N.A. 30.1
Protein Similarity: 100 99.2 71 47.5 N.A. 38.6 74.9 N.A. 26.6 51 N.A. 32 N.A. 47.9 N.A. N.A. 39.6
P-Site Identity: 100 100 6.6 0 N.A. 0 6.6 N.A. 0 6.6 N.A. 6.6 N.A. 13.3 N.A. N.A. 13.3
P-Site Similarity: 100 100 13.3 20 N.A. 13.3 33.3 N.A. 0 40 N.A. 26.6 N.A. 33.3 N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 28 10 0 0 0 10 10 0 28 10 0 19 19 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 10 0 0 0 10 10 0 0 % D
% Glu: 0 10 10 19 0 10 0 0 0 0 10 10 19 10 10 % E
% Phe: 0 0 10 0 10 0 10 10 0 10 0 0 0 0 0 % F
% Gly: 10 10 10 10 10 0 19 0 10 0 10 0 0 19 19 % G
% His: 0 0 10 0 0 0 0 0 0 0 0 0 0 19 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % I
% Lys: 19 10 0 0 0 10 19 0 0 10 0 0 0 10 0 % K
% Leu: 0 0 19 37 0 0 0 10 10 10 0 0 19 0 0 % L
% Met: 0 0 0 0 0 19 0 0 10 0 0 0 0 0 0 % M
% Asn: 0 0 10 0 10 0 0 10 19 0 0 10 10 0 19 % N
% Pro: 37 10 0 0 0 10 19 0 10 10 10 0 10 0 0 % P
% Gln: 10 0 0 0 10 0 0 0 0 0 10 19 0 0 0 % Q
% Arg: 0 0 0 0 0 19 0 0 10 0 0 0 0 19 10 % R
% Ser: 0 19 0 10 19 10 0 37 19 19 10 28 0 0 19 % S
% Thr: 10 0 0 10 19 10 10 0 10 0 28 0 0 0 0 % T
% Val: 0 0 19 10 10 10 10 10 0 10 10 19 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % W
% Tyr: 0 10 0 0 10 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _