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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ICMT
All Species:
14.55
Human Site:
S12
Identified Species:
22.86
UniProt:
O60725
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60725
NP_036537.1
284
31938
S12
A
A
R
A
P
P
G
S
E
A
R
L
S
L
A
Chimpanzee
Pan troglodytes
XP_525166
284
31950
S12
A
A
R
A
P
P
G
S
E
A
R
L
S
L
A
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_546748
284
31977
S12
A
A
R
A
P
P
G
S
E
A
R
L
S
L
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQK7
283
31771
S11
A
R
R
G
S
A
G
S
E
A
R
L
S
L
A
Rat
Rattus norvegicus
Q9WVM4
232
26642
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507547
219
25211
Chicken
Gallus gallus
NP_001006298
297
33156
A25
E
A
R
A
S
L
A
A
F
L
L
G
A
S
V
Frog
Xenopus laevis
O12947
288
32413
S16
E
G
R
V
S
I
V
S
F
T
L
G
A
S
V
Zebra Danio
Brachydanio rerio
Q6ZM63
285
32608
A12
A
Q
L
V
M
G
P
A
G
S
G
K
S
T
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648623
299
34085
C27
E
G
R
I
S
L
Y
C
F
L
I
T
A
A
L
Honey Bee
Apis mellifera
XP_001122123
232
26974
Nematode Worm
Caenorhab. elegans
NP_491473
295
33416
T27
T
S
D
D
V
F
R
T
A
I
F
A
F
I
A
Sea Urchin
Strong. purpuratus
XP_001201998
217
24994
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q93W54
197
22747
Baker's Yeast
Sacchar. cerevisiae
P32584
239
27869
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
N.A.
97.1
N.A.
94.3
76.4
N.A.
68.6
74.7
71.5
20
N.A.
48.1
43.6
35.2
45.7
Protein Similarity:
100
99.6
N.A.
98.5
N.A.
96.4
78.5
N.A.
72.5
82.1
81.9
37.8
N.A.
65.8
59.8
53.5
58.1
P-Site Identity:
100
100
N.A.
100
N.A.
73.3
0
N.A.
0
20
13.3
13.3
N.A.
6.6
0
6.6
0
P-Site Similarity:
100
100
N.A.
100
N.A.
73.3
0
N.A.
0
33.3
20
26.6
N.A.
13.3
0
26.6
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
32.7
31.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.5
47.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
34
27
0
27
0
7
7
14
7
27
0
7
20
7
34
% A
% Cys:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% C
% Asp:
0
0
7
7
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
20
0
0
0
0
0
0
0
27
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
7
0
0
20
0
7
0
7
0
0
% F
% Gly:
0
14
0
7
0
7
27
0
7
0
7
14
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
7
0
7
0
0
0
7
7
0
0
7
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% K
% Leu:
0
0
7
0
0
14
0
0
0
14
14
27
0
27
7
% L
% Met:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
20
20
7
0
0
0
0
0
0
0
0
% P
% Gln:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
7
47
0
0
0
7
0
0
0
27
0
0
0
0
% R
% Ser:
0
7
0
0
27
0
0
34
0
7
0
0
34
14
0
% S
% Thr:
7
0
0
0
0
0
0
7
0
7
0
7
0
7
0
% T
% Val:
0
0
0
14
7
0
7
0
0
0
0
0
0
0
14
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _