Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ICMT All Species: 14.55
Human Site: S12 Identified Species: 22.86
UniProt: O60725 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60725 NP_036537.1 284 31938 S12 A A R A P P G S E A R L S L A
Chimpanzee Pan troglodytes XP_525166 284 31950 S12 A A R A P P G S E A R L S L A
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_546748 284 31977 S12 A A R A P P G S E A R L S L A
Cat Felis silvestris
Mouse Mus musculus Q9EQK7 283 31771 S11 A R R G S A G S E A R L S L A
Rat Rattus norvegicus Q9WVM4 232 26642
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507547 219 25211
Chicken Gallus gallus NP_001006298 297 33156 A25 E A R A S L A A F L L G A S V
Frog Xenopus laevis O12947 288 32413 S16 E G R V S I V S F T L G A S V
Zebra Danio Brachydanio rerio Q6ZM63 285 32608 A12 A Q L V M G P A G S G K S T Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648623 299 34085 C27 E G R I S L Y C F L I T A A L
Honey Bee Apis mellifera XP_001122123 232 26974
Nematode Worm Caenorhab. elegans NP_491473 295 33416 T27 T S D D V F R T A I F A F I A
Sea Urchin Strong. purpuratus XP_001201998 217 24994
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q93W54 197 22747
Baker's Yeast Sacchar. cerevisiae P32584 239 27869
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 N.A. 97.1 N.A. 94.3 76.4 N.A. 68.6 74.7 71.5 20 N.A. 48.1 43.6 35.2 45.7
Protein Similarity: 100 99.6 N.A. 98.5 N.A. 96.4 78.5 N.A. 72.5 82.1 81.9 37.8 N.A. 65.8 59.8 53.5 58.1
P-Site Identity: 100 100 N.A. 100 N.A. 73.3 0 N.A. 0 20 13.3 13.3 N.A. 6.6 0 6.6 0
P-Site Similarity: 100 100 N.A. 100 N.A. 73.3 0 N.A. 0 33.3 20 26.6 N.A. 13.3 0 26.6 0
Percent
Protein Identity: N.A. N.A. N.A. 32.7 31.3 N.A.
Protein Similarity: N.A. N.A. N.A. 47.5 47.5 N.A.
P-Site Identity: N.A. N.A. N.A. 0 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 0 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 34 27 0 27 0 7 7 14 7 27 0 7 20 7 34 % A
% Cys: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % C
% Asp: 0 0 7 7 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 20 0 0 0 0 0 0 0 27 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 7 0 0 20 0 7 0 7 0 0 % F
% Gly: 0 14 0 7 0 7 27 0 7 0 7 14 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 7 0 7 0 0 0 7 7 0 0 7 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % K
% Leu: 0 0 7 0 0 14 0 0 0 14 14 27 0 27 7 % L
% Met: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 20 20 7 0 0 0 0 0 0 0 0 % P
% Gln: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 7 47 0 0 0 7 0 0 0 27 0 0 0 0 % R
% Ser: 0 7 0 0 27 0 0 34 0 7 0 0 34 14 0 % S
% Thr: 7 0 0 0 0 0 0 7 0 7 0 7 0 7 0 % T
% Val: 0 0 0 14 7 0 7 0 0 0 0 0 0 0 14 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _