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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ICMT
All Species:
32.42
Human Site:
S123
Identified Species:
50.95
UniProt:
O60725
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60725
NP_036537.1
284
31938
S123
P
K
S
L
S
L
D
S
F
L
L
N
H
S
L
Chimpanzee
Pan troglodytes
XP_525166
284
31950
S123
P
K
S
L
S
L
D
S
F
L
L
N
H
S
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_546748
284
31977
S123
P
K
S
L
S
L
D
S
F
L
L
N
H
S
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQK7
283
31771
S122
P
K
S
L
S
L
D
S
F
L
L
N
H
S
L
Rat
Rattus norvegicus
Q9WVM4
232
26642
E79
F
L
L
N
H
S
L
E
Y
T
V
A
A
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507547
219
25211
E66
F
L
L
N
H
S
V
E
Y
S
V
A
A
L
S
Chicken
Gallus gallus
NP_001006298
297
33156
S136
P
R
S
L
S
L
D
S
F
L
L
N
H
S
F
Frog
Xenopus laevis
O12947
288
32413
S127
P
R
S
L
S
I
D
S
F
L
L
N
H
S
L
Zebra Danio
Brachydanio rerio
Q6ZM63
285
32608
K121
Y
T
H
L
P
V
M
K
Q
L
V
E
Q
L
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648623
299
34085
S139
P
R
T
L
S
L
D
S
F
M
L
N
H
S
V
Honey Bee
Apis mellifera
XP_001122123
232
26974
A79
F
I
L
N
H
S
I
A
Y
G
V
A
A
C
C
Nematode Worm
Caenorhab. elegans
NP_491473
295
33416
S136
R
R
T
L
G
P
D
S
F
L
L
K
H
S
F
Sea Urchin
Strong. purpuratus
XP_001201998
217
24994
S64
D
S
Y
L
L
N
H
S
I
A
Y
H
V
A
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q93W54
197
22747
S43
G
A
S
K
V
T
L
S
S
L
L
I
S
K
H
Baker's Yeast
Sacchar. cerevisiae
P32584
239
27869
K86
S
F
L
L
N
N
G
K
S
Y
M
A
A
H
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
N.A.
97.1
N.A.
94.3
76.4
N.A.
68.6
74.7
71.5
20
N.A.
48.1
43.6
35.2
45.7
Protein Similarity:
100
99.6
N.A.
98.5
N.A.
96.4
78.5
N.A.
72.5
82.1
81.9
37.8
N.A.
65.8
59.8
53.5
58.1
P-Site Identity:
100
100
N.A.
100
N.A.
100
0
N.A.
0
86.6
86.6
13.3
N.A.
73.3
0
53.3
13.3
P-Site Similarity:
100
100
N.A.
100
N.A.
100
13.3
N.A.
13.3
93.3
100
26.6
N.A.
100
20
66.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
32.7
31.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.5
47.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
0
0
0
7
0
7
0
27
27
7
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
7
% C
% Asp:
7
0
0
0
0
0
54
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
14
0
0
0
7
0
0
0
% E
% Phe:
20
7
0
0
0
0
0
0
54
0
0
0
0
0
14
% F
% Gly:
7
0
0
0
7
0
7
0
0
7
0
0
0
0
0
% G
% His:
0
0
7
0
20
0
7
0
0
0
0
7
54
7
7
% H
% Ile:
0
7
0
0
0
7
7
0
7
0
0
7
0
0
0
% I
% Lys:
0
27
0
7
0
0
0
14
0
0
0
7
0
7
0
% K
% Leu:
0
14
27
74
7
40
14
0
0
60
60
0
0
20
34
% L
% Met:
0
0
0
0
0
0
7
0
0
7
7
0
0
0
0
% M
% Asn:
0
0
0
20
7
14
0
0
0
0
0
47
0
0
0
% N
% Pro:
47
0
0
0
7
7
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
7
0
0
0
7
0
7
% Q
% Arg:
7
27
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
7
7
47
0
47
20
0
67
14
7
0
0
7
54
20
% S
% Thr:
0
7
14
0
0
7
0
0
0
7
0
0
0
0
0
% T
% Val:
0
0
0
0
7
7
7
0
0
0
27
0
7
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
7
0
0
0
0
0
20
7
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _