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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ICMT
All Species:
26.06
Human Site:
S254
Identified Species:
40.95
UniProt:
O60725
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60725
NP_036537.1
284
31938
S254
R
T
E
E
E
E
I
S
L
I
H
F
F
G
E
Chimpanzee
Pan troglodytes
XP_525166
284
31950
S254
R
T
E
E
E
E
I
S
L
I
H
F
F
G
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_546748
284
31977
S254
R
T
E
E
E
E
I
S
L
I
H
F
F
G
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQK7
283
31771
S253
R
T
E
E
E
E
I
S
L
I
H
F
F
G
E
Rat
Rattus norvegicus
Q9WVM4
232
26642
F207
E
I
S
L
I
H
F
F
G
E
E
Y
L
D
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507547
219
25211
F194
E
I
S
L
I
H
F
F
G
E
E
Y
L
E
Y
Chicken
Gallus gallus
NP_001006298
297
33156
T267
R
I
E
E
E
E
I
T
L
I
H
F
F
G
E
Frog
Xenopus laevis
O12947
288
32413
S258
R
I
E
E
E
E
F
S
L
I
H
F
F
G
E
Zebra Danio
Brachydanio rerio
Q6ZM63
285
32608
S251
V
L
Q
H
I
D
F
S
I
Q
Y
G
E
D
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648623
299
34085
S270
R
I
Y
V
E
E
Y
S
L
L
N
F
F
Q
S
Honey Bee
Apis mellifera
XP_001122123
232
26974
F207
E
V
T
L
L
N
F
F
G
Q
D
Y
I
E
Y
Nematode Worm
Caenorhab. elegans
NP_491473
295
33416
D266
R
I
E
I
E
E
K
D
L
I
S
F
F
G
D
Sea Urchin
Strong. purpuratus
XP_001201998
217
24994
A192
D
E
E
I
T
L
I
A
F
F
G
Q
R
Y
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q93W54
197
22747
H172
E
R
I
P
Y
E
E
H
Y
L
K
Q
F
F
G
Baker's Yeast
Sacchar. cerevisiae
P32584
239
27869
E214
S
D
R
I
R
V
E
E
K
Y
L
I
E
F
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
N.A.
97.1
N.A.
94.3
76.4
N.A.
68.6
74.7
71.5
20
N.A.
48.1
43.6
35.2
45.7
Protein Similarity:
100
99.6
N.A.
98.5
N.A.
96.4
78.5
N.A.
72.5
82.1
81.9
37.8
N.A.
65.8
59.8
53.5
58.1
P-Site Identity:
100
100
N.A.
100
N.A.
100
0
N.A.
0
86.6
86.6
6.6
N.A.
46.6
0
60
13.3
P-Site Similarity:
100
100
N.A.
100
N.A.
100
6.6
N.A.
6.6
93.3
86.6
33.3
N.A.
60
6.6
66.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
32.7
31.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.5
47.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
7
0
0
0
7
0
7
0
0
7
0
0
14
7
% D
% Glu:
27
7
54
40
54
60
14
7
0
14
14
0
14
14
40
% E
% Phe:
0
0
0
0
0
0
34
20
7
7
0
54
60
14
7
% F
% Gly:
0
0
0
0
0
0
0
0
20
0
7
7
0
47
7
% G
% His:
0
0
0
7
0
14
0
7
0
0
40
0
0
0
0
% H
% Ile:
0
40
7
20
20
0
40
0
7
47
0
7
7
0
0
% I
% Lys:
0
0
0
0
0
0
7
0
7
0
7
0
0
0
0
% K
% Leu:
0
7
0
20
7
7
0
0
54
14
7
0
14
0
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
7
0
0
0
0
7
0
0
0
0
% N
% Pro:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
7
0
0
0
0
0
0
14
0
14
0
7
0
% Q
% Arg:
54
7
7
0
7
0
0
0
0
0
0
0
7
0
0
% R
% Ser:
7
0
14
0
0
0
0
47
0
0
7
0
0
0
7
% S
% Thr:
0
27
7
0
7
0
0
7
0
0
0
0
0
0
0
% T
% Val:
7
7
0
7
0
7
0
0
0
0
0
0
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
0
7
0
7
0
7
7
7
20
0
7
20
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _