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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ICMT
All Species:
15.76
Human Site:
S86
Identified Species:
24.76
UniProt:
O60725
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60725
NP_036537.1
284
31938
S86
C
G
T
L
L
S
F
S
Q
S
S
W
S
H
F
Chimpanzee
Pan troglodytes
XP_525166
284
31950
S86
C
G
M
L
L
S
F
S
Q
S
S
W
S
H
F
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_546748
284
31977
S86
C
G
M
L
L
S
F
S
Q
S
S
W
N
H
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQK7
283
31771
S85
C
G
V
L
L
S
F
S
Q
S
S
W
N
H
F
Rat
Rattus norvegicus
Q9WVM4
232
26642
G42
Q
S
S
W
N
H
F
G
W
Y
V
C
S
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507547
219
25211
G29
Q
T
S
W
K
H
F
G
W
Y
M
C
S
L
S
Chicken
Gallus gallus
NP_001006298
297
33156
G99
C
G
L
L
L
S
A
G
R
S
A
W
R
H
F
Frog
Xenopus laevis
O12947
288
32413
T90
C
G
L
L
L
S
I
T
Q
S
P
W
K
P
F
Zebra Danio
Brachydanio rerio
Q6ZM63
285
32608
F84
L
I
F
C
M
E
Y
F
S
N
N
F
D
W
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648623
299
34085
A102
S
V
L
V
I
C
F
A
P
T
E
W
Q
Q
F
Honey Bee
Apis mellifera
XP_001122123
232
26974
G42
P
P
S
W
Q
M
F
G
I
Y
I
T
V
L
A
Nematode Worm
Caenorhab. elegans
NP_491473
295
33416
E99
L
V
Y
T
V
A
H
E
G
E
L
W
E
Y
F
Sea Urchin
Strong. purpuratus
XP_001201998
217
24994
P27
F
S
S
N
T
F
H
P
F
G
W
Y
L
V
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q93W54
197
22747
Baker's Yeast
Sacchar. cerevisiae
P32584
239
27869
F49
P
Q
I
R
F
K
N
F
N
L
F
I
I
A
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
N.A.
97.1
N.A.
94.3
76.4
N.A.
68.6
74.7
71.5
20
N.A.
48.1
43.6
35.2
45.7
Protein Similarity:
100
99.6
N.A.
98.5
N.A.
96.4
78.5
N.A.
72.5
82.1
81.9
37.8
N.A.
65.8
59.8
53.5
58.1
P-Site Identity:
100
93.3
N.A.
86.6
N.A.
86.6
13.3
N.A.
13.3
60
60
0
N.A.
20
6.6
13.3
0
P-Site Similarity:
100
93.3
N.A.
93.3
N.A.
93.3
20
N.A.
20
73.3
66.6
33.3
N.A.
46.6
13.3
33.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
32.7
31.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.5
47.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
7
7
7
0
0
7
0
0
7
7
% A
% Cys:
40
0
0
7
0
7
0
0
0
0
0
14
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% D
% Glu:
0
0
0
0
0
7
0
7
0
7
7
0
7
0
0
% E
% Phe:
7
0
7
0
7
7
54
14
7
0
7
7
0
0
54
% F
% Gly:
0
40
0
0
0
0
0
27
7
7
0
0
0
0
0
% G
% His:
0
0
0
0
0
14
14
0
0
0
0
0
0
34
0
% H
% Ile:
0
7
7
0
7
0
7
0
7
0
7
7
7
0
7
% I
% Lys:
0
0
0
0
7
7
0
0
0
0
0
0
7
0
0
% K
% Leu:
14
0
20
40
40
0
0
0
0
7
7
0
7
20
14
% L
% Met:
0
0
14
0
7
7
0
0
0
0
7
0
0
0
0
% M
% Asn:
0
0
0
7
7
0
7
0
7
7
7
0
14
0
0
% N
% Pro:
14
7
0
0
0
0
0
7
7
0
7
0
0
7
0
% P
% Gln:
14
7
0
0
7
0
0
0
34
0
0
0
7
7
0
% Q
% Arg:
0
0
0
7
0
0
0
0
7
0
0
0
7
0
0
% R
% Ser:
7
14
27
0
0
40
0
27
7
40
27
0
27
0
14
% S
% Thr:
0
7
7
7
7
0
0
7
0
7
0
7
0
0
0
% T
% Val:
0
14
7
7
7
0
0
0
0
0
7
0
7
7
0
% V
% Trp:
0
0
0
20
0
0
0
0
14
0
7
54
0
7
0
% W
% Tyr:
0
0
7
0
0
0
7
0
0
20
0
7
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _