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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ICMT
All Species:
30.61
Human Site:
T272
Identified Species:
48.1
UniProt:
O60725
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60725
NP_036537.1
284
31938
T272
E
Y
K
K
R
V
P
T
G
L
P
F
I
K
G
Chimpanzee
Pan troglodytes
XP_525166
284
31950
T272
E
Y
K
K
R
V
P
T
G
L
P
F
I
K
G
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_546748
284
31977
T272
E
Y
K
K
R
V
P
T
G
L
P
F
I
K
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQK7
283
31771
T271
D
Y
K
K
R
V
P
T
G
L
P
F
I
K
G
Rat
Rattus norvegicus
Q9WVM4
232
26642
I225
V
P
T
G
L
P
F
I
K
G
V
K
V
G
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507547
219
25211
I212
V
P
T
G
L
P
F
I
S
G
V
K
V
E
L
Chicken
Gallus gallus
NP_001006298
297
33156
S285
E
Y
K
R
K
V
P
S
G
L
P
F
I
K
G
Frog
Xenopus laevis
O12947
288
32413
T276
E
Y
K
K
K
V
P
T
G
L
P
F
I
K
G
Zebra Danio
Brachydanio rerio
Q6ZM63
285
32608
E269
E
P
K
E
V
D
E
E
P
S
N
S
N
F
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648623
299
34085
T288
R
Y
Q
K
R
V
P
T
G
L
P
F
I
R
G
Honey Bee
Apis mellifera
XP_001122123
232
26974
I225
V
S
T
G
L
P
F
I
S
G
Y
K
L
D
L
Nematode Worm
Caenorhab. elegans
NP_491473
295
33416
S284
E
Y
Q
R
K
T
W
S
G
V
P
F
A
R
G
Sea Urchin
Strong. purpuratus
XP_001201998
217
24994
P210
K
R
V
G
T
M
L
P
F
I
Q
G
Y
K
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q93W54
197
22747
P190
V
E
Y
A
Q
R
V
P
S
G
V
P
F
V
N
Baker's Yeast
Sacchar. cerevisiae
P32584
239
27869
V232
Y
I
E
Y
K
N
K
V
G
V
G
I
P
F
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
N.A.
97.1
N.A.
94.3
76.4
N.A.
68.6
74.7
71.5
20
N.A.
48.1
43.6
35.2
45.7
Protein Similarity:
100
99.6
N.A.
98.5
N.A.
96.4
78.5
N.A.
72.5
82.1
81.9
37.8
N.A.
65.8
59.8
53.5
58.1
P-Site Identity:
100
100
N.A.
100
N.A.
93.3
0
N.A.
0
80
93.3
13.3
N.A.
80
0
40
6.6
P-Site Similarity:
100
100
N.A.
100
N.A.
100
6.6
N.A.
13.3
100
100
20
N.A.
93.3
6.6
80
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
32.7
31.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.5
47.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
0
0
0
0
0
0
0
0
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
0
0
7
0
0
0
0
0
0
0
7
7
% D
% Glu:
47
7
7
7
0
0
7
7
0
0
0
0
0
7
0
% E
% Phe:
0
0
0
0
0
0
20
0
7
0
0
54
7
14
0
% F
% Gly:
0
0
0
27
0
0
0
0
60
27
7
7
0
7
54
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
7
0
0
0
0
0
20
0
7
0
7
47
0
7
% I
% Lys:
7
0
47
40
27
0
7
0
7
0
0
20
0
47
0
% K
% Leu:
0
0
0
0
20
0
7
0
0
47
0
0
7
0
27
% L
% Met:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
7
0
0
0
0
7
0
7
0
7
% N
% Pro:
0
20
0
0
0
20
47
14
7
0
54
7
7
0
0
% P
% Gln:
0
0
14
0
7
0
0
0
0
0
7
0
0
0
0
% Q
% Arg:
7
7
0
14
34
7
0
0
0
0
0
0
0
14
0
% R
% Ser:
0
7
0
0
0
0
0
14
20
7
0
7
0
0
0
% S
% Thr:
0
0
20
0
7
7
0
40
0
0
0
0
0
0
0
% T
% Val:
27
0
7
0
7
47
7
7
0
14
20
0
14
7
0
% V
% Trp:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% W
% Tyr:
7
54
7
7
0
0
0
0
0
0
7
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _