KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ICMT
All Species:
26.36
Human Site:
Y108
Identified Species:
41.43
UniProt:
O60725
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60725
NP_036537.1
284
31938
Y108
S
L
F
H
Y
S
E
Y
L
V
T
A
V
N
N
Chimpanzee
Pan troglodytes
XP_525166
284
31950
Y108
S
L
F
H
Y
S
E
Y
L
V
T
A
V
N
N
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_546748
284
31977
Y108
S
L
F
H
Y
S
E
Y
L
V
T
A
V
N
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQK7
283
31771
Y107
S
L
F
H
Y
S
E
Y
L
V
T
A
V
N
N
Rat
Rattus norvegicus
Q9WVM4
232
26642
P64
L
V
T
T
V
N
N
P
K
S
L
S
L
D
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507547
219
25211
P51
L
V
T
A
V
N
N
P
K
S
L
S
L
D
S
Chicken
Gallus gallus
NP_001006298
297
33156
Y121
S
L
F
H
Y
S
E
Y
L
V
T
A
I
N
N
Frog
Xenopus laevis
O12947
288
32413
Y112
S
F
F
H
Y
S
E
Y
L
V
T
A
M
N
N
Zebra Danio
Brachydanio rerio
Q6ZM63
285
32608
D106
E
D
D
Y
I
L
F
D
C
P
G
Q
I
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648623
299
34085
F124
S
L
F
H
Y
S
E
F
L
V
I
A
F
A
N
Honey Bee
Apis mellifera
XP_001122123
232
26974
P64
L
S
I
A
W
I
N
P
S
S
L
S
I
D
S
Nematode Worm
Caenorhab. elegans
NP_491473
295
33416
F121
S
V
F
H
F
S
E
F
V
F
T
A
L
T
N
Sea Urchin
Strong. purpuratus
XP_001201998
217
24994
Y49
E
F
F
S
T
C
I
Y
N
Y
E
S
L
S
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q93W54
197
22747
Y28
I
F
F
H
T
S
E
Y
I
L
A
I
A
I
H
Baker's Yeast
Sacchar. cerevisiae
P32584
239
27869
N71
Y
Y
I
T
A
K
Y
N
P
L
K
V
H
S
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
N.A.
97.1
N.A.
94.3
76.4
N.A.
68.6
74.7
71.5
20
N.A.
48.1
43.6
35.2
45.7
Protein Similarity:
100
99.6
N.A.
98.5
N.A.
96.4
78.5
N.A.
72.5
82.1
81.9
37.8
N.A.
65.8
59.8
53.5
58.1
P-Site Identity:
100
100
N.A.
100
N.A.
100
0
N.A.
0
93.3
86.6
0
N.A.
73.3
0
53.3
13.3
P-Site Similarity:
100
100
N.A.
100
N.A.
100
40
N.A.
40
100
93.3
13.3
N.A.
80
33.3
86.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
32.7
31.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.5
47.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
14
7
0
0
0
0
0
7
54
7
7
0
% A
% Cys:
0
0
0
0
0
7
0
0
7
0
0
0
0
0
0
% C
% Asp:
0
7
7
0
0
0
0
7
0
0
0
0
0
20
0
% D
% Glu:
14
0
0
0
0
0
60
0
0
0
7
0
0
7
7
% E
% Phe:
0
20
67
0
7
0
7
14
0
7
0
0
7
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% G
% His:
0
0
0
60
0
0
0
0
0
0
0
0
7
0
7
% H
% Ile:
7
0
14
0
7
7
7
0
7
0
7
7
20
7
0
% I
% Lys:
0
0
0
0
0
7
0
0
14
0
7
0
0
0
0
% K
% Leu:
20
40
0
0
0
7
0
0
47
14
20
0
27
0
14
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% M
% Asn:
0
0
0
0
0
14
20
7
7
0
0
0
0
40
54
% N
% Pro:
0
0
0
0
0
0
0
20
7
7
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
54
7
0
7
0
60
0
0
7
20
0
27
0
14
20
% S
% Thr:
0
0
14
14
14
0
0
0
0
0
47
0
0
7
0
% T
% Val:
0
20
0
0
14
0
0
0
7
47
0
7
27
0
0
% V
% Trp:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
7
0
7
47
0
7
54
0
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _