KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ICMT
All Species:
30.91
Human Site:
Y263
Identified Species:
48.57
UniProt:
O60725
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60725
NP_036537.1
284
31938
Y263
I
H
F
F
G
E
E
Y
L
E
Y
K
K
R
V
Chimpanzee
Pan troglodytes
XP_525166
284
31950
Y263
I
H
F
F
G
E
E
Y
L
E
Y
K
K
R
V
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_546748
284
31977
Y263
I
H
F
F
G
E
E
Y
L
E
Y
K
K
R
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQK7
283
31771
Y262
I
H
F
F
G
E
E
Y
L
D
Y
K
K
R
V
Rat
Rattus norvegicus
Q9WVM4
232
26642
K216
E
E
Y
L
D
Y
K
K
R
V
P
T
G
L
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507547
219
25211
K203
E
E
Y
L
E
Y
K
K
K
V
P
T
G
L
P
Chicken
Gallus gallus
NP_001006298
297
33156
Y276
I
H
F
F
G
E
E
Y
L
E
Y
K
R
K
V
Frog
Xenopus laevis
O12947
288
32413
Y267
I
H
F
F
G
E
N
Y
L
E
Y
K
K
K
V
Zebra Danio
Brachydanio rerio
Q6ZM63
285
32608
V260
Q
Y
G
E
D
L
E
V
K
E
P
K
E
V
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648623
299
34085
Y279
L
N
F
F
Q
S
D
Y
V
R
Y
Q
K
R
V
Honey Bee
Apis mellifera
XP_001122123
232
26974
K216
Q
D
Y
I
E
Y
Q
K
E
V
S
T
G
L
P
Nematode Worm
Caenorhab. elegans
NP_491473
295
33416
Y275
I
S
F
F
G
D
D
Y
A
E
Y
Q
R
K
T
Sea Urchin
Strong. purpuratus
XP_001201998
217
24994
Y201
F
G
Q
R
Y
V
D
Y
Q
K
R
V
G
T
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q93W54
197
22747
Q181
L
K
Q
F
F
G
R
Q
Y
V
E
Y
A
Q
R
Baker's Yeast
Sacchar. cerevisiae
P32584
239
27869
A223
Y
L
I
E
F
F
S
A
E
Y
I
E
Y
K
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
N.A.
97.1
N.A.
94.3
76.4
N.A.
68.6
74.7
71.5
20
N.A.
48.1
43.6
35.2
45.7
Protein Similarity:
100
99.6
N.A.
98.5
N.A.
96.4
78.5
N.A.
72.5
82.1
81.9
37.8
N.A.
65.8
59.8
53.5
58.1
P-Site Identity:
100
100
N.A.
100
N.A.
93.3
0
N.A.
0
86.6
86.6
20
N.A.
46.6
0
46.6
6.6
P-Site Similarity:
100
100
N.A.
100
N.A.
100
13.3
N.A.
13.3
100
93.3
33.3
N.A.
80
13.3
80
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
32.7
31.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.5
47.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
7
7
0
0
0
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
0
0
14
7
20
0
0
7
0
0
0
0
7
% D
% Glu:
14
14
0
14
14
40
40
0
14
47
7
7
7
0
0
% E
% Phe:
7
0
54
60
14
7
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
7
7
0
47
7
0
0
0
0
0
0
27
0
0
% G
% His:
0
40
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
47
0
7
7
0
0
0
0
0
0
7
0
0
0
0
% I
% Lys:
0
7
0
0
0
0
14
20
14
7
0
47
40
27
0
% K
% Leu:
14
7
0
14
0
7
0
0
40
0
0
0
0
20
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% M
% Asn:
0
7
0
0
0
0
7
0
0
0
0
0
0
0
7
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
20
0
0
0
20
% P
% Gln:
14
0
14
0
7
0
7
7
7
0
0
14
0
7
0
% Q
% Arg:
0
0
0
7
0
0
7
0
7
7
7
0
14
34
7
% R
% Ser:
0
7
0
0
0
7
7
0
0
0
7
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
20
0
7
7
% T
% Val:
0
0
0
0
0
7
0
7
7
27
0
7
0
7
47
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
7
20
0
7
20
0
60
7
7
54
7
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _