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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDC14B
All Species:
1.52
Human Site:
S401
Identified Species:
5.56
UniProt:
O60729
Number Species:
6
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60729
NP_003662.1
498
56802
S401
L
S
G
V
D
D
I
S
I
N
G
V
E
N
Q
Chimpanzee
Pan troglodytes
XP_001152444
495
56317
D398
S
K
L
L
S
G
V
D
D
I
S
I
N
G
N
Rhesus Macaque
Macaca mulatta
XP_001106436
461
52266
I365
S
G
V
D
D
I
S
I
N
G
V
E
N
Q
D
Dog
Lupus familis
XP_533499
653
73322
R557
W
L
E
G
D
Y
F
R
Q
K
L
R
G
Q
E
Cat
Felis silvestris
Mouse
Mus musculus
Q6PFY9
485
55643
P385
L
R
G
Q
E
N
G
P
L
R
E
A
F
S
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_425045
527
60015
G401
V
G
H
I
S
I
N
G
I
R
N
R
R
T
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q00684
551
61888
T453
I
N
N
N
R
N
P
T
S
H
A
N
R
K
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.7
90.1
62.4
N.A.
79.7
N.A.
N.A.
N.A.
59.5
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
97.7
91.3
67.3
N.A.
87.5
N.A.
N.A.
N.A.
74.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
6.6
6.6
N.A.
13.3
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
6.6
13.3
N.A.
46.6
N.A.
N.A.
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
30.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
15
15
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
15
43
15
0
15
15
0
0
0
0
0
15
% D
% Glu:
0
0
15
0
15
0
0
0
0
0
15
15
15
0
15
% E
% Phe:
0
0
0
0
0
0
15
0
0
0
0
0
15
0
0
% F
% Gly:
0
29
29
15
0
15
15
15
0
15
15
0
15
15
0
% G
% His:
0
0
15
0
0
0
0
0
0
15
0
0
0
0
0
% H
% Ile:
15
0
0
15
0
29
15
15
29
15
0
15
0
0
15
% I
% Lys:
0
15
0
0
0
0
0
0
0
15
0
0
0
15
15
% K
% Leu:
29
15
15
15
0
0
0
0
15
0
15
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
15
15
15
0
29
15
0
15
15
15
15
29
15
15
% N
% Pro:
0
0
0
0
0
0
15
15
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
15
0
0
0
0
15
0
0
0
0
29
15
% Q
% Arg:
0
15
0
0
15
0
0
15
0
29
0
29
29
0
0
% R
% Ser:
29
15
0
0
29
0
15
15
15
0
15
0
0
15
0
% S
% Thr:
0
0
0
0
0
0
0
15
0
0
0
0
0
15
0
% T
% Val:
15
0
15
15
0
0
15
0
0
0
15
15
0
0
15
% V
% Trp:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
15
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _