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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLA2G6
All Species:
7.27
Human Site:
S445
Identified Species:
20
UniProt:
O60733
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60733
NP_001004426.1
806
89903
S445
R
A
Q
P
P
P
I
S
L
N
N
L
E
L
Q
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_850251
836
92917
S475
R
S
Q
P
P
P
I
S
L
N
N
L
E
L
Q
Cat
Felis silvestris
Mouse
Mus musculus
P97819
752
83684
S404
L
Q
D
L
M
P
I
S
R
A
R
K
P
A
F
Rat
Rattus norvegicus
P97570
751
83564
S403
L
Q
D
L
M
P
V
S
R
A
R
K
P
A
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001124210
796
88378
L436
P
R
S
S
S
N
S
L
G
Y
K
D
L
L
Y
Frog
Xenopus laevis
NP_001086854
756
84285
S408
V
Y
V
S
T
A
L
S
G
M
L
V
P
Q
D
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_394049
798
88142
R438
Q
P
P
K
A
I
P
R
T
I
L
D
Q
M
L
Nematode Worm
Caenorhab. elegans
NP_508000
1023
114506
E620
L
G
S
S
S
S
D
E
Q
S
M
E
D
R
V
Sea Urchin
Strong. purpuratus
XP_781913
745
81575
E395
T
G
R
Q
G
K
D
E
T
D
D
H
M
D
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
87.5
N.A.
85.1
84.1
N.A.
N.A.
62.1
57.5
N.A.
N.A.
N.A.
36
24.5
34.3
Protein Similarity:
100
N.A.
N.A.
91
N.A.
89
88.2
N.A.
N.A.
77.6
73.9
N.A.
N.A.
N.A.
56.9
43.8
51.3
P-Site Identity:
100
N.A.
N.A.
93.3
N.A.
20
13.3
N.A.
N.A.
6.6
6.6
N.A.
N.A.
N.A.
0
0
0
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
20
20
N.A.
N.A.
6.6
20
N.A.
N.A.
N.A.
20
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
0
0
12
12
0
0
0
23
0
0
0
23
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
23
0
0
0
23
0
0
12
12
23
12
12
12
% D
% Glu:
0
0
0
0
0
0
0
23
0
0
0
12
23
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
23
% F
% Gly:
0
23
0
0
12
0
0
0
23
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% H
% Ile:
0
0
0
0
0
12
34
0
0
12
0
0
0
0
0
% I
% Lys:
0
0
0
12
0
12
0
0
0
0
12
23
0
0
0
% K
% Leu:
34
0
0
23
0
0
12
12
23
0
23
23
12
34
12
% L
% Met:
0
0
0
0
23
0
0
0
0
12
12
0
12
12
0
% M
% Asn:
0
0
0
0
0
12
0
0
0
23
23
0
0
0
0
% N
% Pro:
12
12
12
23
23
45
12
0
0
0
0
0
34
0
0
% P
% Gln:
12
23
23
12
0
0
0
0
12
0
0
0
12
12
23
% Q
% Arg:
23
12
12
0
0
0
0
12
23
0
23
0
0
12
0
% R
% Ser:
0
12
23
34
23
12
12
56
0
12
0
0
0
0
0
% S
% Thr:
12
0
0
0
12
0
0
0
23
0
0
0
0
0
12
% T
% Val:
12
0
12
0
0
0
12
0
0
0
0
12
0
0
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
12
0
0
0
0
0
0
0
12
0
0
0
0
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _