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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLA2G6
All Species:
5.76
Human Site:
S458
Identified Species:
15.83
UniProt:
O60733
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60733
NP_001004426.1
806
89903
S458
L
Q
D
L
M
H
I
S
R
A
R
K
P
A
F
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_850251
836
92917
S488
L
Q
D
I
V
Q
I
S
R
S
R
K
P
A
F
Cat
Felis silvestris
Mouse
Mus musculus
P97819
752
83684
R417
A
F
I
L
S
S
M
R
D
E
K
R
S
H
D
Rat
Rattus norvegicus
P97570
751
83564
R416
A
F
I
L
S
S
M
R
D
E
K
R
T
H
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001124210
796
88378
G449
L
Y
V
S
A
T
L
G
Q
F
L
K
A
P
D
Frog
Xenopus laevis
NP_001086854
756
84285
E421
Q
D
T
V
D
F
R
E
D
G
L
R
V
K
D
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_394049
798
88142
D451
M
L
H
V
S
G
M
D
K
M
A
T
Q
E
N
Nematode Worm
Caenorhab. elegans
NP_508000
1023
114506
S633
R
V
K
D
I
H
V
S
D
N
A
A
S
A
P
Sea Urchin
Strong. purpuratus
XP_781913
745
81575
N408
D
T
T
D
G
A
S
N
P
S
Q
R
R
S
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
87.5
N.A.
85.1
84.1
N.A.
N.A.
62.1
57.5
N.A.
N.A.
N.A.
36
24.5
34.3
Protein Similarity:
100
N.A.
N.A.
91
N.A.
89
88.2
N.A.
N.A.
77.6
73.9
N.A.
N.A.
N.A.
56.9
43.8
51.3
P-Site Identity:
100
N.A.
N.A.
73.3
N.A.
6.6
6.6
N.A.
N.A.
13.3
0
N.A.
N.A.
N.A.
0
20
0
P-Site Similarity:
100
N.A.
N.A.
93.3
N.A.
26.6
26.6
N.A.
N.A.
26.6
13.3
N.A.
N.A.
N.A.
26.6
33.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
23
0
0
0
12
12
0
0
0
12
23
12
12
34
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
12
12
23
23
12
0
0
12
45
0
0
0
0
0
45
% D
% Glu:
0
0
0
0
0
0
0
12
0
23
0
0
0
12
0
% E
% Phe:
0
23
0
0
0
12
0
0
0
12
0
0
0
0
23
% F
% Gly:
0
0
0
0
12
12
0
12
0
12
0
0
0
0
0
% G
% His:
0
0
12
0
0
23
0
0
0
0
0
0
0
23
0
% H
% Ile:
0
0
23
12
12
0
23
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
12
0
0
0
0
0
12
0
23
34
0
12
0
% K
% Leu:
34
12
0
34
0
0
12
0
0
0
23
0
0
0
0
% L
% Met:
12
0
0
0
12
0
34
0
0
12
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
12
0
12
0
0
0
0
12
% N
% Pro:
0
0
0
0
0
0
0
0
12
0
0
0
23
12
12
% P
% Gln:
12
23
0
0
0
12
0
0
12
0
12
0
12
0
12
% Q
% Arg:
12
0
0
0
0
0
12
23
23
0
23
45
12
0
0
% R
% Ser:
0
0
0
12
34
23
12
34
0
23
0
0
23
12
0
% S
% Thr:
0
12
23
0
0
12
0
0
0
0
0
12
12
0
0
% T
% Val:
0
12
12
23
12
0
12
0
0
0
0
0
12
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _