KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLA2G6
All Species:
8.18
Human Site:
Y254
Identified Species:
22.5
UniProt:
O60733
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60733
NP_001004426.1
806
89903
Y254
N
I
M
G
P
N
G
Y
P
I
H
S
A
M
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_850251
836
92917
Y284
N
I
M
G
P
T
G
Y
P
I
H
T
A
M
K
Cat
Felis silvestris
Mouse
Mus musculus
P97819
752
83684
K229
T
P
L
H
L
A
C
K
M
G
K
Q
E
M
V
Rat
Rattus norvegicus
P97570
751
83564
Q228
T
P
L
H
L
A
C
Q
M
G
K
Q
E
M
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001124210
796
88378
Y245
N
V
M
G
T
V
G
Y
P
I
H
A
A
L
K
Frog
Xenopus laevis
NP_001086854
756
84285
G231
L
H
V
A
C
R
L
G
K
T
E
L
V
L
A
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_394049
798
88142
N249
L
L
I
G
A
D
V
N
I
P
A
S
E
G
Q
Nematode Worm
Caenorhab. elegans
NP_508000
1023
114506
I426
S
T
Q
M
A
N
P
I
I
G
A
M
K
R
G
Sea Urchin
Strong. purpuratus
XP_781913
745
81575
K218
Q
V
M
T
V
L
S
K
D
K
E
L
M
D
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
87.5
N.A.
85.1
84.1
N.A.
N.A.
62.1
57.5
N.A.
N.A.
N.A.
36
24.5
34.3
Protein Similarity:
100
N.A.
N.A.
91
N.A.
89
88.2
N.A.
N.A.
77.6
73.9
N.A.
N.A.
N.A.
56.9
43.8
51.3
P-Site Identity:
100
N.A.
N.A.
86.6
N.A.
6.6
6.6
N.A.
N.A.
66.6
0
N.A.
N.A.
N.A.
13.3
6.6
6.6
P-Site Similarity:
100
N.A.
N.A.
93.3
N.A.
13.3
13.3
N.A.
N.A.
86.6
13.3
N.A.
N.A.
N.A.
40
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
12
23
23
0
0
0
0
23
12
34
0
12
% A
% Cys:
0
0
0
0
12
0
23
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
12
0
0
12
0
0
0
0
12
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
23
0
34
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
45
0
0
34
12
0
34
0
0
0
12
12
% G
% His:
0
12
0
23
0
0
0
0
0
0
34
0
0
0
0
% H
% Ile:
0
23
12
0
0
0
0
12
23
34
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
23
12
12
23
0
12
0
34
% K
% Leu:
23
12
23
0
23
12
12
0
0
0
0
23
0
23
0
% L
% Met:
0
0
45
12
0
0
0
0
23
0
0
12
12
45
0
% M
% Asn:
34
0
0
0
0
23
0
12
0
0
0
0
0
0
0
% N
% Pro:
0
23
0
0
23
0
12
0
34
12
0
0
0
0
0
% P
% Gln:
12
0
12
0
0
0
0
12
0
0
0
23
0
0
12
% Q
% Arg:
0
0
0
0
0
12
0
0
0
0
0
0
0
12
12
% R
% Ser:
12
0
0
0
0
0
12
0
0
0
0
23
0
0
0
% S
% Thr:
23
12
0
12
12
12
0
0
0
12
0
12
0
0
0
% T
% Val:
0
23
12
0
12
12
12
0
0
0
0
0
12
0
23
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
34
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _