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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF1B
All Species:
20.61
Human Site:
S9
Identified Species:
34.87
UniProt:
O60739
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60739
NP_005866.1
113
12824
S9
S
T
I
Q
N
L
Q
S
F
D
P
F
A
D
A
Chimpanzee
Pan troglodytes
XP_001135309
107
12202
S9
S
T
I
Q
N
L
Q
S
F
D
P
F
A
D
A
Rhesus Macaque
Macaca mulatta
XP_001092971
375
42014
S271
S
A
I
Q
N
L
H
S
F
D
P
F
A
D
A
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P48024
113
12728
S9
S
A
I
Q
N
L
H
S
F
D
P
F
A
D
A
Rat
Rattus norvegicus
XP_575765
113
12659
S9
S
A
I
Q
N
L
H
S
F
D
P
F
A
D
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516708
105
11888
H24
A
G
T
E
D
Y
I
H
I
R
I
Q
Q
R
N
Chicken
Gallus gallus
P51971
79
8986
Frog
Xenopus laevis
NP_001080047
113
12556
P9
S
A
I
Q
N
L
Q
P
F
D
P
F
V
N
A
Zebra Danio
Brachydanio rerio
NP_956597
113
12854
S9
S
N
I
Q
N
L
Q
S
F
D
P
F
A
D
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VZS3
110
12432
R9
S
I
Q
N
L
N
T
R
D
P
F
A
D
A
I
Honey Bee
Apis mellifera
XP_392601
110
12369
F9
S
I
Q
N
L
N
T
F
D
P
F
A
D
A
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P56330
115
12686
A11
L
D
I
Q
I
P
T
A
F
D
P
F
A
E
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94JV4
113
12572
P9
S
D
L
E
V
Q
V
P
T
A
F
D
P
F
A
Baker's Yeast
Sacchar. cerevisiae
P32911
108
12294
I28
A
T
S
N
Y
I
H
I
R
I
Q
Q
R
N
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.5
28
N.A.
N.A.
92
91.1
N.A.
92
64.5
81.4
96.4
N.A.
69
69.9
N.A.
N.A.
Protein Similarity:
100
92
29.8
N.A.
N.A.
97.3
96.4
N.A.
92.9
69
89.3
97.3
N.A.
84
83.1
N.A.
N.A.
P-Site Identity:
100
100
86.6
N.A.
N.A.
86.6
86.6
N.A.
0
0
73.3
93.3
N.A.
6.6
6.6
N.A.
N.A.
P-Site Similarity:
100
100
86.6
N.A.
N.A.
86.6
86.6
N.A.
20
0
80
93.3
N.A.
6.6
6.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
56.5
N.A.
55.7
60.1
N.A.
Protein Similarity:
N.A.
77.3
N.A.
78.7
80.5
N.A.
P-Site Identity:
N.A.
53.3
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
66.6
N.A.
26.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
29
0
0
0
0
0
8
0
8
0
15
50
15
65
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
15
0
0
8
0
0
0
15
58
0
8
15
43
0
% D
% Glu:
0
0
0
15
0
0
0
0
0
0
0
0
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
8
58
0
22
58
0
8
0
% F
% Gly:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
29
8
0
0
0
0
0
0
0
% H
% Ile:
0
15
58
0
8
8
8
8
8
8
8
0
0
0
15
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
8
0
8
0
15
50
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
22
50
15
0
0
0
0
0
0
0
15
8
% N
% Pro:
0
0
0
0
0
8
0
15
0
15
58
0
8
0
0
% P
% Gln:
0
0
15
58
0
8
29
0
0
0
8
15
8
0
0
% Q
% Arg:
0
0
0
0
0
0
0
8
8
8
0
0
8
8
0
% R
% Ser:
72
0
8
0
0
0
0
43
0
0
0
0
0
0
0
% S
% Thr:
0
22
8
0
0
0
22
0
8
0
0
0
0
0
0
% T
% Val:
0
0
0
0
8
0
8
0
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _