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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF1B
All Species:
38.79
Human Site:
T43
Identified Species:
65.64
UniProt:
O60739
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60739
NP_005866.1
113
12824
T43
Q
Q
R
N
G
R
K
T
L
T
T
V
Q
G
I
Chimpanzee
Pan troglodytes
XP_001135309
107
12202
T43
Q
Q
R
N
G
R
K
T
L
T
T
V
Q
G
I
Rhesus Macaque
Macaca mulatta
XP_001092971
375
42014
T305
Q
Q
R
N
G
R
K
T
L
T
T
V
Q
G
I
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P48024
113
12728
T43
Q
Q
R
N
G
R
K
T
L
T
T
V
Q
G
I
Rat
Rattus norvegicus
XP_575765
113
12659
T43
Q
Q
R
N
G
R
K
T
L
T
T
V
Q
G
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516708
105
11888
K58
L
V
K
A
F
K
K
K
F
A
C
N
G
T
V
Chicken
Gallus gallus
P51971
79
8986
V39
K
F
A
C
N
G
T
V
I
E
H
P
E
Y
G
Frog
Xenopus laevis
NP_001080047
113
12556
T43
Q
Q
R
N
G
R
K
T
L
T
T
V
Q
G
I
Zebra Danio
Brachydanio rerio
NP_956597
113
12854
T43
Q
Q
R
N
G
R
K
T
L
T
T
V
Q
G
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VZS3
110
12432
T43
N
G
R
K
T
L
T
T
V
Q
G
L
S
A
E
Honey Bee
Apis mellifera
XP_392601
110
12369
T43
N
G
R
K
T
L
T
T
V
Q
G
L
S
S
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P56330
115
12686
S45
Q
Q
R
N
G
R
K
S
L
T
T
V
Q
G
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94JV4
113
12572
S43
Q
Q
R
N
G
R
K
S
L
T
T
V
Q
G
L
Baker's Yeast
Sacchar. cerevisiae
P32911
108
12294
F62
L
K
V
L
K
K
D
F
A
C
N
G
N
I
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.5
28
N.A.
N.A.
92
91.1
N.A.
92
64.5
81.4
96.4
N.A.
69
69.9
N.A.
N.A.
Protein Similarity:
100
92
29.8
N.A.
N.A.
97.3
96.4
N.A.
92.9
69
89.3
97.3
N.A.
84
83.1
N.A.
N.A.
P-Site Identity:
100
100
100
N.A.
N.A.
100
100
N.A.
6.6
0
100
100
N.A.
13.3
13.3
N.A.
N.A.
P-Site Similarity:
100
100
100
N.A.
N.A.
100
100
N.A.
26.6
20
100
100
N.A.
26.6
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
56.5
N.A.
55.7
60.1
N.A.
Protein Similarity:
N.A.
77.3
N.A.
78.7
80.5
N.A.
P-Site Identity:
N.A.
86.6
N.A.
86.6
0
N.A.
P-Site Similarity:
N.A.
100
N.A.
100
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
0
0
0
0
8
8
0
0
0
8
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
8
8
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
8
0
0
8
0
15
% E
% Phe:
0
8
0
0
8
0
0
8
8
0
0
0
0
0
0
% F
% Gly:
0
15
0
0
65
8
0
0
0
0
15
8
8
65
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
8
0
0
0
0
8
50
% I
% Lys:
8
8
8
15
8
15
72
8
0
0
0
0
0
0
0
% K
% Leu:
15
0
0
8
0
15
0
0
65
0
0
15
0
0
15
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
15
0
0
65
8
0
0
0
0
0
8
8
8
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% P
% Gln:
65
65
0
0
0
0
0
0
0
15
0
0
65
0
0
% Q
% Arg:
0
0
79
0
0
65
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
15
0
0
0
0
15
8
0
% S
% Thr:
0
0
0
0
15
0
22
65
0
65
65
0
0
8
0
% T
% Val:
0
8
8
0
0
0
0
8
15
0
0
65
0
0
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _