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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF1B
All Species:
36.36
Human Site:
Y79
Identified Species:
61.54
UniProt:
O60739
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60739
NP_005866.1
113
12824
Y79
T
V
I
E
H
P
E
Y
G
E
V
I
Q
L
Q
Chimpanzee
Pan troglodytes
XP_001135309
107
12202
Y79
T
V
I
E
H
P
E
Y
G
E
V
I
Q
L
Q
Rhesus Macaque
Macaca mulatta
XP_001092971
375
42014
Y341
T
V
I
E
H
P
E
Y
G
E
V
I
Q
L
Q
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P48024
113
12728
Y79
T
V
I
E
H
P
E
Y
G
E
V
I
Q
L
Q
Rat
Rattus norvegicus
XP_575765
113
12659
Y79
T
V
I
E
H
P
E
Y
G
E
V
I
Q
L
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516708
105
11888
E91
N
I
C
Q
F
L
L
E
V
G
I
V
K
E
E
Chicken
Gallus gallus
P51971
79
8986
D72
E
I
G
L
A
K
D
D
Q
L
K
V
H
G
F
Frog
Xenopus laevis
NP_001080047
113
12556
Y79
T
V
V
D
H
P
E
Y
G
E
V
I
Q
L
Q
Zebra Danio
Brachydanio rerio
NP_956597
113
12854
Y79
T
V
I
E
H
P
E
Y
G
E
V
I
Q
L
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VZS3
110
12432
Y76
T
V
I
E
H
P
E
Y
G
E
V
L
Q
L
Q
Honey Bee
Apis mellifera
XP_392601
110
12369
Y76
T
V
I
E
H
P
E
Y
G
E
V
L
Q
L
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P56330
115
12686
L81
T
V
V
Q
D
P
E
L
G
Q
V
I
Q
L
Q
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94JV4
113
12572
L79
T
V
V
Q
D
S
E
L
G
Q
V
I
Q
L
Q
Baker's Yeast
Sacchar. cerevisiae
P32911
108
12294
Q99
M
I
S
Q
L
G
L
Q
K
K
N
I
K
I
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.5
28
N.A.
N.A.
92
91.1
N.A.
92
64.5
81.4
96.4
N.A.
69
69.9
N.A.
N.A.
Protein Similarity:
100
92
29.8
N.A.
N.A.
97.3
96.4
N.A.
92.9
69
89.3
97.3
N.A.
84
83.1
N.A.
N.A.
P-Site Identity:
100
100
100
N.A.
N.A.
100
100
N.A.
0
0
86.6
100
N.A.
93.3
93.3
N.A.
N.A.
P-Site Similarity:
100
100
100
N.A.
N.A.
100
100
N.A.
40
20
100
100
N.A.
100
100
N.A.
N.A.
Percent
Protein Identity:
N.A.
56.5
N.A.
55.7
60.1
N.A.
Protein Similarity:
N.A.
77.3
N.A.
78.7
80.5
N.A.
P-Site Identity:
N.A.
66.6
N.A.
60
6.6
N.A.
P-Site Similarity:
N.A.
86.6
N.A.
80
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
15
0
8
8
0
0
0
0
0
0
0
% D
% Glu:
8
0
0
58
0
0
79
8
0
65
0
0
0
8
8
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
0
0
8
0
0
8
0
0
79
8
0
0
0
8
0
% G
% His:
0
0
0
0
65
0
0
0
0
0
0
0
8
0
8
% H
% Ile:
0
22
58
0
0
0
0
0
0
0
8
72
0
8
0
% I
% Lys:
0
0
0
0
0
8
0
0
8
8
8
0
15
0
0
% K
% Leu:
0
0
0
8
8
8
15
15
0
8
0
15
0
79
0
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% N
% Pro:
0
0
0
0
0
72
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
29
0
0
0
8
8
15
0
0
79
0
79
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
8
0
0
8
0
0
0
0
0
0
0
0
0
% S
% Thr:
79
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
79
22
0
0
0
0
0
8
0
79
15
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
65
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _