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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DPM1 All Species: 27.27
Human Site: T172 Identified Species: 50
UniProt: O60762 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60762 NP_003850.1 260 29634 T172 S R G A N F L T Q I L L R P G
Chimpanzee Pan troglodytes XP_001168321 260 29632 T172 S R G A N F L T Q I L L R P G
Rhesus Macaque Macaca mulatta XP_001094366 260 29601 T172 S R G A N F L T Q I L L R P G
Dog Lupus familis XP_534456 260 29402 T172 S R G A N F L T Q I L L R P G
Cat Felis silvestris
Mouse Mus musculus O70152 260 29156 T172 S R G A N F I T Q I L L R P G
Rat Rattus norvegicus NP_001100014 260 29231 T172 S R G A N F I T Q I L L R P G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_417511 242 27177 Q155 R G A N F I T Q V L L R P G A
Frog Xenopus laevis NP_001089465 247 27775 Q160 R G A N F I T Q V L L R P G A
Zebra Danio Brachydanio rerio NP_001003596 250 28114 Q163 R G A N F V T Q V L L R P G A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VIU7 241 26984 Q154 R G A N F L S Q V L L R P N A
Honey Bee Apis mellifera XP_392640 253 29018 T165 S R G A N F L T Q L L L R P G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_793909 242 27148 Q155 R G A N F L A Q V L L R P G A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P14020 267 30344 D176 L E N C N P R D I N S Q G F K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 97.3 96.5 N.A. 91.1 91.1 N.A. N.A. 83.8 82.3 81.9 N.A. 68.8 70.3 N.A. 75.3
Protein Similarity: 100 99.6 98.8 98 N.A. 94.6 95.3 N.A. N.A. 90 91.9 91.5 N.A. 81.5 86.1 N.A. 85.3
P-Site Identity: 100 100 100 100 N.A. 93.3 93.3 N.A. N.A. 6.6 6.6 6.6 N.A. 6.6 93.3 N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 13.3 13.3 13.3 N.A. 13.3 100 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 32.2 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 49.4 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 39 54 0 0 8 0 0 0 0 0 0 0 39 % A
% Cys: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % D
% Glu: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 39 54 0 0 0 0 0 0 0 8 0 % F
% Gly: 0 39 54 0 0 0 0 0 0 0 0 0 8 31 54 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 16 16 0 8 47 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % K
% Leu: 8 0 0 0 0 16 39 0 0 47 93 54 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 8 39 62 0 0 0 0 8 0 0 0 8 0 % N
% Pro: 0 0 0 0 0 8 0 0 0 0 0 0 39 54 0 % P
% Gln: 0 0 0 0 0 0 0 39 54 0 0 8 0 0 0 % Q
% Arg: 39 54 0 0 0 0 8 0 0 0 0 39 54 0 0 % R
% Ser: 54 0 0 0 0 0 8 0 0 0 8 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 24 54 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 8 0 0 39 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _