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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DPM1
All Species:
27.27
Human Site:
Y190
Identified Species:
50
UniProt:
O60762
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.42
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60762
NP_003850.1
260
29634
Y190
L
T
G
S
F
R
L
Y
R
K
E
V
L
E
K
Chimpanzee
Pan troglodytes
XP_001168321
260
29632
Y190
L
T
G
S
F
R
L
Y
R
K
E
V
L
E
K
Rhesus Macaque
Macaca mulatta
XP_001094366
260
29601
Y190
L
T
G
S
F
R
L
Y
R
K
E
V
L
E
K
Dog
Lupus familis
XP_534456
260
29402
Y190
L
T
G
S
F
R
L
Y
R
K
E
V
L
Q
K
Cat
Felis silvestris
Mouse
Mus musculus
O70152
260
29156
Y190
L
T
G
S
F
R
L
Y
R
K
E
V
L
Q
K
Rat
Rattus norvegicus
NP_001100014
260
29231
Y190
L
T
G
S
F
R
L
Y
R
K
E
V
L
Q
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417511
242
27177
R173
T
G
S
F
R
L
Y
R
K
E
V
L
E
K
L
Frog
Xenopus laevis
NP_001089465
247
27775
R178
T
G
S
F
R
L
Y
R
K
D
V
L
Q
K
L
Zebra Danio
Brachydanio rerio
NP_001003596
250
28114
K181
T
G
S
F
R
L
Y
K
K
E
V
L
E
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VIU7
241
26984
K172
T
G
S
F
R
L
Y
K
K
D
V
L
E
K
C
Honey Bee
Apis mellifera
XP_392640
253
29018
Y183
L
T
G
S
F
R
L
Y
K
K
D
V
L
E
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793909
242
27148
K173
T
G
S
F
R
L
Y
K
K
E
V
L
Q
R
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P14020
267
30344
L194
E
L
L
A
K
L
P
L
P
R
D
P
R
V
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
97.3
96.5
N.A.
91.1
91.1
N.A.
N.A.
83.8
82.3
81.9
N.A.
68.8
70.3
N.A.
75.3
Protein Similarity:
100
99.6
98.8
98
N.A.
94.6
95.3
N.A.
N.A.
90
91.9
91.5
N.A.
81.5
86.1
N.A.
85.3
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
0
0
0
N.A.
0
86.6
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
26.6
20
26.6
N.A.
20
100
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
32.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
49.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
0
0
0
0
0
0
0
0
0
16
16
0
0
0
0
% D
% Glu:
8
0
0
0
0
0
0
0
0
24
47
0
24
31
0
% E
% Phe:
0
0
0
39
54
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
39
54
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
8
0
0
24
47
54
0
0
0
31
54
% K
% Leu:
54
8
8
0
0
47
54
8
0
0
0
39
54
0
31
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
8
0
8
0
0
8
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
16
24
0
% Q
% Arg:
0
0
0
0
39
54
0
16
47
8
0
0
8
8
0
% R
% Ser:
0
0
39
54
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
39
54
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
39
54
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
39
54
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _