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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DPM1 All Species: 27.27
Human Site: Y236 Identified Species: 50
UniProt: O60762 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60762 NP_003850.1 260 29634 Y236 I S F V D R V Y G E S K L G G
Chimpanzee Pan troglodytes XP_001168321 260 29632 Y236 I S F V D R V Y G E S K L G G
Rhesus Macaque Macaca mulatta XP_001094366 260 29601 Y236 I S F V D R V Y G E S K L G G
Dog Lupus familis XP_534456 260 29402 Y236 I S F V D R V Y G E S K L G G
Cat Felis silvestris
Mouse Mus musculus O70152 260 29156 Y236 I S F V D R V Y G E S K L G G
Rat Rattus norvegicus NP_001100014 260 29231 Y236 I S F V D R V Y G E S K L G G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_417511 242 27177 G219 S F V D R V Y G E S K L G G N
Frog Xenopus laevis NP_001089465 247 27775 G224 S F V D R V Y G E S K L G G N
Zebra Danio Brachydanio rerio NP_001003596 250 28114 G227 S F V D R V Y G E S K L G G N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VIU7 241 26984 G218 T F V D R I Y G T S K L G G T
Honey Bee Apis mellifera XP_392640 253 29018 Y229 I T F V D R L Y G E S K L G G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_793909 242 27148 G219 T F V D R F Y G E S K L G G S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P14020 267 30344 G240 E L Y V F K F G A N N L I L F
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 97.3 96.5 N.A. 91.1 91.1 N.A. N.A. 83.8 82.3 81.9 N.A. 68.8 70.3 N.A. 75.3
Protein Similarity: 100 99.6 98.8 98 N.A. 94.6 95.3 N.A. N.A. 90 91.9 91.5 N.A. 81.5 86.1 N.A. 85.3
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. N.A. 6.6 6.6 6.6 N.A. 6.6 86.6 N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 6.6 6.6 6.6 N.A. 6.6 100 N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 32.2 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 49.4 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 39 54 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 8 0 0 0 0 0 0 0 31 54 0 0 0 0 0 % E
% Phe: 0 39 54 0 8 8 8 0 0 0 0 0 0 0 8 % F
% Gly: 0 0 0 0 0 0 0 47 54 0 0 0 39 93 54 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 54 0 0 0 0 8 0 0 0 0 0 0 8 0 0 % I
% Lys: 0 0 0 0 0 8 0 0 0 0 39 54 0 0 0 % K
% Leu: 0 8 0 0 0 0 8 0 0 0 0 47 54 8 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 8 8 0 0 0 24 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 39 54 0 0 0 0 0 0 0 0 0 % R
% Ser: 24 47 0 0 0 0 0 0 0 39 54 0 0 0 8 % S
% Thr: 16 8 0 0 0 0 0 0 8 0 0 0 0 0 8 % T
% Val: 0 0 39 62 0 24 47 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 0 0 0 39 54 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _