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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: USO1 All Species: 12.73
Human Site: S758 Identified Species: 28
UniProt: O60763 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60763 NP_003706.1 962 107895 S758 S Q L T E K D S M I E N M K S
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001100598 962 107800 S758 S K L T E K D S V I E N L K S
Dog Lupus familis XP_535607 963 107794 L759 Q L A E K N S L I E N L K S S
Cat Felis silvestris
Mouse Mus musculus Q9Z1Z0 959 106965 S758 G Q L A E K D S L I E N L K S
Rat Rattus norvegicus P41542 959 107144 T758 S Q L A E K D T V I E N L R S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510418 1009 113386 A800 G Q L E E K D A L I E S L R S
Chicken Gallus gallus NP_001026310 952 106140 G752 N R H E Q L Q G Q L K E K D A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002660510 956 107343 Q754 R L E E V Q R Q N Q L L Q T Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_395962 838 94098 N647 G S S L H N K N Q I T T P I L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana B0F9L4 914 101816 A721 D Y I N R L K A F I E K Q C S
Baker's Yeast Sacchar. cerevisiae P25386 1790 206434 L1468 N K R D L E S L K E Q L R A A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 98.8 94.6 N.A. 92.3 91.8 N.A. 79.9 81 N.A. 74.4 N.A. N.A. 46 N.A. N.A.
Protein Similarity: 100 N.A. 99.5 97.7 N.A. 95.6 95.8 N.A. 88.4 90.2 N.A. 87.4 N.A. N.A. 64.7 N.A. N.A.
P-Site Identity: 100 N.A. 80 6.6 N.A. 73.3 66.6 N.A. 53.3 0 N.A. 0 N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: 100 N.A. 100 20 N.A. 86.6 93.3 N.A. 86.6 40 N.A. 6.6 N.A. N.A. 13.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 24.8 22.5 N.A.
Protein Similarity: N.A. N.A. N.A. 45.6 36.7 N.A.
P-Site Identity: N.A. N.A. N.A. 20 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 19 0 0 0 19 0 0 0 0 0 10 19 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % C
% Asp: 10 0 0 10 0 0 46 0 0 0 0 0 0 10 0 % D
% Glu: 0 0 10 37 46 10 0 0 0 19 55 10 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % F
% Gly: 28 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % G
% His: 0 0 10 0 10 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 10 0 0 0 0 0 10 64 0 0 0 10 0 % I
% Lys: 0 19 0 0 10 46 19 0 10 0 10 10 19 28 0 % K
% Leu: 0 19 46 10 10 19 0 19 19 10 10 28 37 0 10 % L
% Met: 0 0 0 0 0 0 0 0 10 0 0 0 10 0 0 % M
% Asn: 19 0 0 10 0 19 0 10 10 0 10 37 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % P
% Gln: 10 37 0 0 10 10 10 10 19 10 10 0 19 0 10 % Q
% Arg: 10 10 10 0 10 0 10 0 0 0 0 0 10 19 0 % R
% Ser: 28 10 10 0 0 0 19 28 0 0 0 10 0 10 64 % S
% Thr: 0 0 0 19 0 0 0 10 0 0 10 10 0 10 0 % T
% Val: 0 0 0 0 10 0 0 0 19 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _