Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: USO1 All Species: 11.82
Human Site: S780 Identified Species: 26
UniProt: O60763 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.3
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60763 NP_003706.1 962 107895 S780 E Q S S A I V S A R D S E Q V
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001100598 962 107800 S780 E Q S S A I V S A R D S E Q V
Dog Lupus familis XP_535607 963 107794 S781 E Q S S A T A S A R D S E Q I
Cat Felis silvestris
Mouse Mus musculus Q9Z1Z0 959 106965 P780 E Q A S A T C P P R D P E Q V
Rat Rattus norvegicus P41542 959 107144 S780 E Q A L A T C S P R D A E Q V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510418 1009 113386 K822 E T S L E A F K A G D S E N T
Chicken Gallus gallus NP_001026310 952 106140 E774 L Q V E M G T E Q S S Q L S S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002660510 956 107343 G776 I T S L K A E G V P S V E D S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_395962 838 94098 E669 Q Y K E V I R E Q D S Q I Q K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana B0F9L4 914 101816 D743 R N A A L A E D V A S S G R N
Baker's Yeast Sacchar. cerevisiae P25386 1790 206434 E1490 E E G L K K L E E E S S K E K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 98.8 94.6 N.A. 92.3 91.8 N.A. 79.9 81 N.A. 74.4 N.A. N.A. 46 N.A. N.A.
Protein Similarity: 100 N.A. 99.5 97.7 N.A. 95.6 95.8 N.A. 88.4 90.2 N.A. 87.4 N.A. N.A. 64.7 N.A. N.A.
P-Site Identity: 100 N.A. 100 80 N.A. 60 60 N.A. 40 6.6 N.A. 13.3 N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: 100 N.A. 100 86.6 N.A. 66.6 73.3 N.A. 40 6.6 N.A. 13.3 N.A. N.A. 20 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 24.8 22.5 N.A.
Protein Similarity: N.A. N.A. N.A. 45.6 36.7 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 28 10 46 28 10 0 37 10 0 10 0 0 0 % A
% Cys: 0 0 0 0 0 0 19 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 10 0 10 55 0 0 10 0 % D
% Glu: 64 10 0 19 10 0 19 28 10 10 0 0 64 10 0 % E
% Phe: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 10 0 0 10 0 10 0 10 0 0 10 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 0 0 0 0 28 0 0 0 0 0 0 10 0 10 % I
% Lys: 0 0 10 0 19 10 0 10 0 0 0 0 10 0 19 % K
% Leu: 10 0 0 37 10 0 10 0 0 0 0 0 10 0 0 % L
% Met: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 10 0 0 0 0 0 0 0 0 0 0 0 10 10 % N
% Pro: 0 0 0 0 0 0 0 10 19 10 0 10 0 0 0 % P
% Gln: 10 55 0 0 0 0 0 0 19 0 0 19 0 55 0 % Q
% Arg: 10 0 0 0 0 0 10 0 0 46 0 0 0 10 0 % R
% Ser: 0 0 46 37 0 0 0 37 0 10 46 55 0 10 19 % S
% Thr: 0 19 0 0 0 28 10 0 0 0 0 0 0 0 10 % T
% Val: 0 0 10 0 10 0 19 0 19 0 0 10 0 0 37 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _