KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC19A2
All Species:
1.52
Human Site:
S244
Identified Species:
4.17
UniProt:
O60779
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60779
NP_008927.1
497
55400
S244
I
V
T
D
T
P
A
S
N
H
L
P
G
W
E
Chimpanzee
Pan troglodytes
XP_526049
496
55539
L244
I
L
S
T
S
G
K
L
N
K
G
Q
L
N
S
Rhesus Macaque
Macaca mulatta
XP_001093667
495
55135
N258
I
E
S
K
I
P
L
N
M
E
E
P
P
L
E
Dog
Lupus familis
XP_850843
459
51571
M227
V
P
S
T
C
Q
R
M
N
G
I
K
E
P
K
Cat
Felis silvestris
Mouse
Mus musculus
Q99PL8
488
55054
S244
N
L
E
D
R
E
M
S
N
P
D
P
E
N
S
Rat
Rattus norvegicus
Q62866
512
58076
V275
R
L
W
C
L
W
W
V
F
N
S
A
G
Y
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002662367
478
53350
K244
P
E
D
P
E
S
N
K
Q
P
N
T
L
K
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q17766
410
46514
A178
V
C
L
V
T
I
I
A
I
F
L
P
R
V
K
Sea Urchin
Strong. purpuratus
XP_791719
533
60255
L248
R
S
I
K
E
R
T
L
S
C
F
S
S
T
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
49.2
98.3
86.5
N.A.
48.6
38.4
N.A.
N.A.
N.A.
N.A.
56.5
N.A.
N.A.
N.A.
28.7
42.5
Protein Similarity:
100
66.5
99.1
89.5
N.A.
64.5
57
N.A.
N.A.
N.A.
N.A.
70.2
N.A.
N.A.
N.A.
49.2
58.3
P-Site Identity:
100
13.3
26.6
6.6
N.A.
26.6
6.6
N.A.
N.A.
N.A.
N.A.
0
N.A.
N.A.
N.A.
20
0
P-Site Similarity:
100
33.3
40
33.3
N.A.
33.3
26.6
N.A.
N.A.
N.A.
N.A.
0
N.A.
N.A.
N.A.
40
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
12
12
0
0
0
12
0
0
0
% A
% Cys:
0
12
0
12
12
0
0
0
0
12
0
0
0
0
0
% C
% Asp:
0
0
12
23
0
0
0
0
0
0
12
0
0
0
0
% D
% Glu:
0
23
12
0
23
12
0
0
0
12
12
0
23
0
23
% E
% Phe:
0
0
0
0
0
0
0
0
12
12
12
0
0
0
0
% F
% Gly:
0
0
0
0
0
12
0
0
0
12
12
0
23
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% H
% Ile:
34
0
12
0
12
12
12
0
12
0
12
0
0
0
0
% I
% Lys:
0
0
0
23
0
0
12
12
0
12
0
12
0
12
34
% K
% Leu:
0
34
12
0
12
0
12
23
0
0
23
0
23
12
0
% L
% Met:
0
0
0
0
0
0
12
12
12
0
0
0
0
0
0
% M
% Asn:
12
0
0
0
0
0
12
12
45
12
12
0
0
23
0
% N
% Pro:
12
12
0
12
0
23
0
0
0
23
0
45
12
12
0
% P
% Gln:
0
0
0
0
0
12
0
0
12
0
0
12
0
0
0
% Q
% Arg:
23
0
0
0
12
12
12
0
0
0
0
0
12
0
0
% R
% Ser:
0
12
34
0
12
12
0
23
12
0
12
12
12
0
34
% S
% Thr:
0
0
12
23
23
0
12
0
0
0
0
12
0
12
0
% T
% Val:
23
12
0
12
0
0
0
12
0
0
0
0
0
12
0
% V
% Trp:
0
0
12
0
0
12
12
0
0
0
0
0
0
12
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _