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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC19A2
All Species:
4.85
Human Site:
S255
Identified Species:
13.33
UniProt:
O60779
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60779
NP_008927.1
497
55400
S255
P
G
W
E
D
I
E
S
K
I
P
L
N
M
E
Chimpanzee
Pan troglodytes
XP_526049
496
55539
S255
Q
L
N
S
L
K
S
S
N
V
T
V
D
V
F
Rhesus Macaque
Macaca mulatta
XP_001093667
495
55135
P269
P
P
L
E
E
P
E
P
K
P
D
R
L
L
V
Dog
Lupus familis
XP_850843
459
51571
L238
K
E
P
K
P
D
R
L
L
V
L
K
I
L
W
Cat
Felis silvestris
Mouse
Mus musculus
Q99PL8
488
55054
H255
P
E
N
S
A
L
R
H
F
A
H
W
F
Q
D
Rat
Rattus norvegicus
Q62866
512
58076
Y286
A
G
Y
Y
L
I
T
Y
Y
V
H
V
L
W
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002662367
478
53350
S255
T
L
K
S
N
T
S
S
S
G
L
L
D
V
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q17766
410
46514
A189
P
R
V
K
S
E
K
A
K
V
S
M
R
A
H
Sea Urchin
Strong. purpuratus
XP_791719
533
60255
H259
S
S
T
K
R
F
S
H
Y
L
W
A
D
F
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
49.2
98.3
86.5
N.A.
48.6
38.4
N.A.
N.A.
N.A.
N.A.
56.5
N.A.
N.A.
N.A.
28.7
42.5
Protein Similarity:
100
66.5
99.1
89.5
N.A.
64.5
57
N.A.
N.A.
N.A.
N.A.
70.2
N.A.
N.A.
N.A.
49.2
58.3
P-Site Identity:
100
6.6
26.6
0
N.A.
6.6
13.3
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
13.3
0
P-Site Similarity:
100
33.3
40
20
N.A.
20
40
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
N.A.
46.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
0
12
0
0
12
0
12
0
12
0
12
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
12
12
0
0
0
0
12
0
34
0
12
% D
% Glu:
0
23
0
23
12
12
23
0
0
0
0
0
0
0
12
% E
% Phe:
0
0
0
0
0
12
0
0
12
0
0
0
12
12
12
% F
% Gly:
0
23
0
0
0
0
0
0
0
12
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
23
0
0
23
0
0
0
12
% H
% Ile:
0
0
0
0
0
23
0
0
0
12
0
0
12
0
0
% I
% Lys:
12
0
12
34
0
12
12
0
34
0
0
12
0
0
23
% K
% Leu:
0
23
12
0
23
12
0
12
12
12
23
23
23
23
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
12
0
12
0
% M
% Asn:
0
0
23
0
12
0
0
0
12
0
0
0
12
0
0
% N
% Pro:
45
12
12
0
12
12
0
12
0
12
12
0
0
0
0
% P
% Gln:
12
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% Q
% Arg:
0
12
0
0
12
0
23
0
0
0
0
12
12
0
0
% R
% Ser:
12
12
0
34
12
0
34
34
12
0
12
0
0
0
0
% S
% Thr:
12
0
12
0
0
12
12
0
0
0
12
0
0
0
0
% T
% Val:
0
0
12
0
0
0
0
0
0
45
0
23
0
23
12
% V
% Trp:
0
0
12
0
0
0
0
0
0
0
12
12
0
12
12
% W
% Tyr:
0
0
12
12
0
0
0
12
23
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _