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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC19A2
All Species:
4.55
Human Site:
S490
Identified Species:
12.5
UniProt:
O60779
Number Species:
8
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60779
NP_008927.1
497
55400
S490
R
K
L
E
D
P
Q
S
S
S
Q
V
T
T
S
Chimpanzee
Pan troglodytes
XP_526049
496
55539
P473
S
Q
K
D
V
Q
S
P
A
P
S
E
N
P
G
Rhesus Macaque
Macaca mulatta
XP_001093667
495
55135
S488
R
K
L
E
D
P
E
S
S
S
Q
V
T
T
S
Dog
Lupus familis
XP_850843
459
51571
Cat
Felis silvestris
Mouse
Mus musculus
Q99PL8
488
55054
E475
A
T
T
R
S
P
N
E
P
H
P
Q
E
P
S
Rat
Rattus norvegicus
Q62866
512
58076
D505
S
V
E
D
G
R
A
D
L
R
V
E
A
K
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002662367
478
53350
Q470
S
S
R
T
S
G
G
Q
N
E
L
S
S
A
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q17766
410
46514
Sea Urchin
Strong. purpuratus
XP_791719
533
60255
C474
C
R
Q
T
L
S
C
C
H
G
N
N
G
A
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
49.2
98.3
86.5
N.A.
48.6
38.4
N.A.
N.A.
N.A.
N.A.
56.5
N.A.
N.A.
N.A.
28.7
42.5
Protein Similarity:
100
66.5
99.1
89.5
N.A.
64.5
57
N.A.
N.A.
N.A.
N.A.
70.2
N.A.
N.A.
N.A.
49.2
58.3
P-Site Identity:
100
0
93.3
0
N.A.
13.3
0
N.A.
N.A.
N.A.
N.A.
0
N.A.
N.A.
N.A.
0
0
P-Site Similarity:
100
20
100
0
N.A.
13.3
13.3
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
0
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
0
0
0
12
0
12
0
0
0
12
23
12
% A
% Cys:
12
0
0
0
0
0
12
12
0
0
0
0
0
0
12
% C
% Asp:
0
0
0
23
23
0
0
12
0
0
0
0
0
0
0
% D
% Glu:
0
0
12
23
0
0
12
12
0
12
0
23
12
0
12
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
12
12
12
0
0
12
0
0
12
0
12
% G
% His:
0
0
0
0
0
0
0
0
12
12
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
23
12
0
0
0
0
0
0
0
0
0
0
12
0
% K
% Leu:
0
0
23
0
12
0
0
0
12
0
12
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
12
0
12
0
12
12
12
0
0
% N
% Pro:
0
0
0
0
0
34
0
12
12
12
12
0
0
23
0
% P
% Gln:
0
12
12
0
0
12
12
12
0
0
23
12
0
0
0
% Q
% Arg:
23
12
12
12
0
12
0
0
0
12
0
0
0
0
0
% R
% Ser:
34
12
0
0
23
12
12
23
23
23
12
12
12
0
34
% S
% Thr:
0
12
12
23
0
0
0
0
0
0
0
0
23
23
0
% T
% Val:
0
12
0
0
12
0
0
0
0
0
12
23
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _