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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC19A2 All Species: 3.94
Human Site: T239 Identified Species: 10.83
UniProt: O60779 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60779 NP_008927.1 497 55400 T239 V Q N G G I V T D T P A S N H
Chimpanzee Pan troglodytes XP_526049 496 55539 S239 K P T S E I L S T S G K L N K
Rhesus Macaque Macaca mulatta XP_001093667 495 55135 S253 P G W E D I E S K I P L N M E
Dog Lupus familis XP_850843 459 51571 S222 L F F H H V P S T C Q R M N G
Cat Felis silvestris
Mouse Mus musculus Q99PL8 488 55054 E239 F A N S K N L E D R E M S N P
Rat Rattus norvegicus Q62866 512 58076 W270 R Q P Q L R L W C L W W V F N
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002662367 478 53350 D239 P L I E K P E D P E S N K Q P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q17766 410 46514 L173 I S L G A V C L V T I I A I F
Sea Urchin Strong. purpuratus XP_791719 533 60255 I243 S K P P L R S I K E R T L S C
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 49.2 98.3 86.5 N.A. 48.6 38.4 N.A. N.A. N.A. N.A. 56.5 N.A. N.A. N.A. 28.7 42.5
Protein Similarity: 100 66.5 99.1 89.5 N.A. 64.5 57 N.A. N.A. N.A. N.A. 70.2 N.A. N.A. N.A. 49.2 58.3
P-Site Identity: 100 13.3 13.3 6.6 N.A. 26.6 6.6 N.A. N.A. N.A. N.A. 0 N.A. N.A. N.A. 13.3 0
P-Site Similarity: 100 33.3 26.6 26.6 N.A. 33.3 20 N.A. N.A. N.A. N.A. 0 N.A. N.A. N.A. 33.3 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 12 0 0 12 0 0 0 0 0 0 12 12 0 0 % A
% Cys: 0 0 0 0 0 0 12 0 12 12 0 0 0 0 12 % C
% Asp: 0 0 0 0 12 0 0 12 23 0 0 0 0 0 0 % D
% Glu: 0 0 0 23 12 0 23 12 0 23 12 0 0 0 12 % E
% Phe: 12 12 12 0 0 0 0 0 0 0 0 0 0 12 12 % F
% Gly: 0 12 0 23 12 0 0 0 0 0 12 0 0 0 12 % G
% His: 0 0 0 12 12 0 0 0 0 0 0 0 0 0 12 % H
% Ile: 12 0 12 0 0 34 0 12 0 12 12 12 0 12 0 % I
% Lys: 12 12 0 0 23 0 0 0 23 0 0 12 12 0 12 % K
% Leu: 12 12 12 0 23 0 34 12 0 12 0 12 23 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 12 12 12 0 % M
% Asn: 0 0 23 0 0 12 0 0 0 0 0 12 12 45 12 % N
% Pro: 23 12 23 12 0 12 12 0 12 0 23 0 0 0 23 % P
% Gln: 0 23 0 12 0 0 0 0 0 0 12 0 0 12 0 % Q
% Arg: 12 0 0 0 0 23 0 0 0 12 12 12 0 0 0 % R
% Ser: 12 12 0 23 0 0 12 34 0 12 12 0 23 12 0 % S
% Thr: 0 0 12 0 0 0 0 12 23 23 0 12 0 0 0 % T
% Val: 12 0 0 0 0 23 12 0 12 0 0 0 12 0 0 % V
% Trp: 0 0 12 0 0 0 0 12 0 0 12 12 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _