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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC19A2 All Species: 0.91
Human Site: T54 Identified Species: 2.5
UniProt: O60779 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0.5
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60779 NP_008927.1 497 55400 T54 R P S E P F L T P Y L L G P D
Chimpanzee Pan troglodytes XP_526049 496 55539 E54 T S A E I T N E I F P I W T Y
Rhesus Macaque Macaca mulatta XP_001093667 495 55135 E64 G P D K N L S E R E V F N E I
Dog Lupus familis XP_850843 459 51571 C38 F L P T A L L C A Y G F F A S
Cat Felis silvestris
Mouse Mus musculus Q99PL8 488 55054 E55 T S P E M T N E I L P V W T Y
Rat Rattus norvegicus Q62866 512 58076 E65 T K E Q V T N E I I P M L P Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002662367 478 53350 P55 L M P F L M G P D K N L T E T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q17766 410 46514
Sea Urchin Strong. purpuratus XP_791719 533 60255 Y59 Y P V W T Y T Y M V A L I F V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 49.2 98.3 86.5 N.A. 48.6 38.4 N.A. N.A. N.A. N.A. 56.5 N.A. N.A. N.A. 28.7 42.5
Protein Similarity: 100 66.5 99.1 89.5 N.A. 64.5 57 N.A. N.A. N.A. N.A. 70.2 N.A. N.A. N.A. 49.2 58.3
P-Site Identity: 100 6.6 6.6 13.3 N.A. 6.6 6.6 N.A. N.A. N.A. N.A. 6.6 N.A. N.A. N.A. 0 13.3
P-Site Similarity: 100 26.6 20 13.3 N.A. 13.3 20 N.A. N.A. N.A. N.A. 6.6 N.A. N.A. N.A. 0 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 12 0 12 0 0 0 12 0 12 0 0 12 0 % A
% Cys: 0 0 0 0 0 0 0 12 0 0 0 0 0 0 0 % C
% Asp: 0 0 12 0 0 0 0 0 12 0 0 0 0 0 12 % D
% Glu: 0 0 12 34 0 0 0 45 0 12 0 0 0 23 0 % E
% Phe: 12 0 0 12 0 12 0 0 0 12 0 23 12 12 0 % F
% Gly: 12 0 0 0 0 0 12 0 0 0 12 0 12 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 12 0 0 0 34 12 0 12 12 0 12 % I
% Lys: 0 12 0 12 0 0 0 0 0 12 0 0 0 0 0 % K
% Leu: 12 12 0 0 12 23 23 0 0 12 12 34 12 0 0 % L
% Met: 0 12 0 0 12 12 0 0 12 0 0 12 0 0 0 % M
% Asn: 0 0 0 0 12 0 34 0 0 0 12 0 12 0 0 % N
% Pro: 0 34 34 0 12 0 0 12 12 0 34 0 0 23 0 % P
% Gln: 0 0 0 12 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 12 0 0 0 0 0 0 0 12 0 0 0 0 0 0 % R
% Ser: 0 23 12 0 0 0 12 0 0 0 0 0 0 0 12 % S
% Thr: 34 0 0 12 12 34 12 12 0 0 0 0 12 23 12 % T
% Val: 0 0 12 0 12 0 0 0 0 12 12 12 0 0 12 % V
% Trp: 0 0 0 12 0 0 0 0 0 0 0 0 23 0 0 % W
% Tyr: 12 0 0 0 0 12 0 12 0 23 0 0 0 0 34 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _