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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CCDC22 All Species: 16.06
Human Site: S361 Identified Species: 29.44
UniProt: O60826 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60826 NP_054727.1 627 70756 S361 D M K T L G V S F V Q A E S E
Chimpanzee Pan troglodytes XP_001143086 331 38131 R88 A E R E Q A L R L K S R A V E
Rhesus Macaque Macaca mulatta XP_001106217 627 70698 S361 D M K T L G V S F V Q A E S E
Dog Lupus familis XP_548995 627 70779 S361 N M K T L G I S L M Q V E T E
Cat Felis silvestris
Mouse Mus musculus Q9JIG7 627 70825 N361 D M K T L G I N L V Q V E T E
Rat Rattus norvegicus P86182 627 70836 N361 N M K S L G M N L V Q V E T E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q6PA15 632 72232 T366 S N K L L Q L T I G Q V E G E
Zebra Danio Brachydanio rerio Q4V909 639 71968 S373 G I K Q L T V S I Q Q V T D E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VVB4 555 62995 L312 I S R I Q P T L K L H E R T S
Honey Bee Apis mellifera XP_395711 557 64268 K314 K N L T T S I K A R I Y D L F
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795944 639 73126 S373 E S K Q L G A S V Q Q M E E Q
Poplar Tree Populus trichocarpa XP_002298881 518 58714 K275 E E E L E L L K A A A E M A Y
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_175979 412 47939 S169 S Q L C S L E S E L E L L Q M
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 52.7 98.4 91.5 N.A. 88 87.7 N.A. N.A. N.A. 53.6 56.3 N.A. 30.9 33.4 N.A. 44.2
Protein Similarity: 100 52.7 98.7 95 N.A. 92 92.1 N.A. N.A. N.A. 69.9 73.2 N.A. 48.1 56.9 N.A. 62.4
P-Site Identity: 100 6.6 100 60 N.A. 66.6 53.3 N.A. N.A. N.A. 33.3 40 N.A. 0 6.6 N.A. 40
P-Site Similarity: 100 20 100 86.6 N.A. 86.6 86.6 N.A. N.A. N.A. 46.6 46.6 N.A. 20 20 N.A. 53.3
Percent
Protein Identity: 26.9 N.A. N.A. 23.4 N.A. N.A.
Protein Similarity: 43.8 N.A. N.A. 39.8 N.A. N.A.
P-Site Identity: 0 N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: 26.6 N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 0 8 8 0 16 8 8 16 8 8 0 % A
% Cys: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 24 0 0 0 0 0 0 0 0 0 0 0 8 8 0 % D
% Glu: 16 16 8 8 8 0 8 0 8 0 8 16 54 8 62 % E
% Phe: 0 0 0 0 0 0 0 0 16 0 0 0 0 0 8 % F
% Gly: 8 0 0 0 0 47 0 0 0 8 0 0 0 8 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % H
% Ile: 8 8 0 8 0 0 24 0 16 0 8 0 0 0 0 % I
% Lys: 8 0 62 0 0 0 0 16 8 8 0 0 0 0 0 % K
% Leu: 0 0 16 16 62 16 24 8 31 16 0 8 8 8 0 % L
% Met: 0 39 0 0 0 0 8 0 0 8 0 8 8 0 8 % M
% Asn: 16 16 0 0 0 0 0 16 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 8 0 16 16 8 0 0 0 16 62 0 0 8 8 % Q
% Arg: 0 0 16 0 0 0 0 8 0 8 0 8 8 0 0 % R
% Ser: 16 16 0 8 8 8 0 47 0 0 8 0 0 16 8 % S
% Thr: 0 0 0 39 8 8 8 8 0 0 0 0 8 31 0 % T
% Val: 0 0 0 0 0 0 24 0 8 31 0 39 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _