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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DKC1
All Species:
46.06
Human Site:
S387
Identified Species:
72.38
UniProt:
O60832
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60832
NP_001354.1
514
57674
S387
W
G
L
G
P
K
A
S
Q
K
K
L
M
I
K
Chimpanzee
Pan troglodytes
XP_521345
595
65925
S468
M
C
K
G
K
K
A
S
Q
K
K
L
M
I
K
Rhesus Macaque
Macaca mulatta
XP_001090867
597
66468
S470
W
G
L
G
P
K
A
S
Q
K
K
L
M
I
K
Dog
Lupus familis
XP_549382
517
57997
S387
W
G
L
G
P
K
A
S
Q
K
R
L
M
I
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9ESX5
509
57483
S387
W
G
L
G
P
K
A
S
Q
K
K
M
M
I
K
Rat
Rattus norvegicus
P40615
509
56597
S388
W
G
L
G
P
K
A
S
Q
K
K
Q
L
I
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514686
519
58453
S389
W
G
L
G
P
K
A
S
Q
K
K
L
M
I
K
Chicken
Gallus gallus
Q5ZJH9
516
58132
S385
W
G
L
G
P
K
A
S
Q
K
K
M
M
I
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001028279
506
56658
S382
W
G
L
G
P
K
A
S
Q
K
K
M
M
I
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O44081
508
56812
S385
W
G
L
G
P
K
A
S
A
K
K
A
L
I
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O17919
445
50192
A330
I
M
S
T
K
G
E
A
I
C
I
A
I
A
Q
Sea Urchin
Strong. purpuratus
XP_001187533
541
60439
S380
W
G
L
G
P
K
A
S
M
K
K
T
M
I
K
Poplar Tree
Populus trichocarpa
XP_002323264
482
54054
W367
R
D
T
Y
P
R
K
W
G
L
G
P
K
A
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LD90
565
63008
S378
W
G
L
G
P
R
A
S
M
K
K
K
L
I
A
Baker's Yeast
Sacchar. cerevisiae
P33322
483
54686
Q357
W
G
L
G
P
V
A
Q
K
K
K
Q
M
K
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.3
85.5
89.9
N.A.
90
83.2
N.A.
85.3
81.4
N.A.
74.7
N.A.
64.7
N.A.
58.7
64.8
Protein Similarity:
100
85.3
86
93.6
N.A.
93.1
90.8
N.A.
88.8
89.9
N.A.
85.4
N.A.
77.6
N.A.
71.4
77
P-Site Identity:
100
73.3
100
93.3
N.A.
93.3
86.6
N.A.
100
86.6
N.A.
86.6
N.A.
73.3
N.A.
0
86.6
P-Site Similarity:
100
73.3
100
100
N.A.
100
93.3
N.A.
100
100
N.A.
100
N.A.
80
N.A.
20
86.6
Percent
Protein Identity:
61.2
N.A.
N.A.
57.5
57.9
N.A.
Protein Similarity:
76.4
N.A.
N.A.
73.4
71.9
N.A.
P-Site Identity:
6.6
N.A.
N.A.
66.6
60
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
80
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
87
7
7
0
0
14
0
14
20
% A
% Cys:
0
7
0
0
0
0
0
0
0
7
0
0
0
0
0
% C
% Asp:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
80
0
87
0
7
0
0
7
0
7
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
7
0
0
0
0
0
0
0
7
0
7
0
7
80
0
% I
% Lys:
0
0
7
0
14
74
7
0
7
87
80
7
7
7
54
% K
% Leu:
0
0
80
0
0
0
0
0
0
7
0
34
20
0
0
% L
% Met:
7
7
0
0
0
0
0
0
14
0
0
20
67
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
87
0
0
0
0
0
0
7
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
7
60
0
0
14
0
0
20
% Q
% Arg:
7
0
0
0
0
14
0
0
0
0
7
0
0
0
0
% R
% Ser:
0
0
7
0
0
0
0
80
0
0
0
0
0
0
7
% S
% Thr:
0
0
7
7
0
0
0
0
0
0
0
7
0
0
0
% T
% Val:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% V
% Trp:
80
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _