KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DKC1
All Species:
25.45
Human Site:
T67
Identified Species:
40
UniProt:
O60832
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60832
NP_001354.1
514
57674
T67
D
K
L
N
V
R
T
T
H
Y
T
P
L
A
C
Chimpanzee
Pan troglodytes
XP_521345
595
65925
T148
D
K
L
N
V
R
T
T
H
Y
T
P
L
A
C
Rhesus Macaque
Macaca mulatta
XP_001090867
597
66468
T150
D
K
L
N
V
R
T
T
H
Y
T
P
L
A
C
Dog
Lupus familis
XP_549382
517
57997
T67
D
K
L
N
V
R
T
T
H
Y
T
P
L
P
C
Cat
Felis silvestris
Mouse
Mus musculus
Q9ESX5
509
57483
A67
D
K
L
N
V
R
T
A
H
Y
T
P
L
P
C
Rat
Rattus norvegicus
P40615
509
56597
T68
D
R
L
N
V
R
T
T
H
Y
T
P
I
P
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514686
519
58453
T69
D
K
L
N
V
R
T
T
H
Y
T
P
L
P
S
Chicken
Gallus gallus
Q5ZJH9
516
58132
T65
D
K
L
N
V
L
T
T
H
Y
T
P
L
P
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001028279
506
56658
A62
D
K
L
N
I
R
T
A
H
Y
T
P
L
P
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O44081
508
56812
N65
D
K
L
N
I
R
S
N
H
Y
T
P
L
A
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O17919
445
50192
S28
K
G
S
F
Q
L
P
S
S
N
E
T
A
K
L
Sea Urchin
Strong. purpuratus
XP_001187533
541
60439
G60
D
K
L
N
I
R
T
G
H
Y
T
P
L
P
N
Poplar Tree
Populus trichocarpa
XP_002323264
482
54054
G54
D
R
L
N
V
R
T
G
H
Y
T
P
L
P
C
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LD90
565
63008
G58
D
R
L
N
V
R
T
G
H
Y
T
P
I
S
A
Baker's Yeast
Sacchar. cerevisiae
P33322
483
54686
D52
G
S
S
P
L
K
R
D
L
K
S
Y
I
S
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.3
85.5
89.9
N.A.
90
83.2
N.A.
85.3
81.4
N.A.
74.7
N.A.
64.7
N.A.
58.7
64.8
Protein Similarity:
100
85.3
86
93.6
N.A.
93.1
90.8
N.A.
88.8
89.9
N.A.
85.4
N.A.
77.6
N.A.
71.4
77
P-Site Identity:
100
100
100
93.3
N.A.
86.6
80
N.A.
86.6
80
N.A.
73.3
N.A.
73.3
N.A.
0
73.3
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
93.3
N.A.
86.6
80
N.A.
80
N.A.
86.6
N.A.
6.6
80
Percent
Protein Identity:
61.2
N.A.
N.A.
57.5
57.9
N.A.
Protein Similarity:
76.4
N.A.
N.A.
73.4
71.9
N.A.
P-Site Identity:
80
N.A.
N.A.
66.6
0
N.A.
P-Site Similarity:
86.6
N.A.
N.A.
86.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
14
0
0
0
0
7
27
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
47
% C
% Asp:
87
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% E
% Phe:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
7
7
0
0
0
0
0
20
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
87
0
0
0
0
0
14
% H
% Ile:
0
0
0
0
20
0
0
0
0
0
0
0
20
0
0
% I
% Lys:
7
67
0
0
0
7
0
0
0
7
0
0
0
7
0
% K
% Leu:
0
0
87
0
7
14
0
0
7
0
0
0
74
0
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
87
0
0
0
7
0
7
0
0
0
0
7
% N
% Pro:
0
0
0
7
0
0
7
0
0
0
0
87
0
54
0
% P
% Gln:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
20
0
0
0
80
7
0
0
0
0
0
0
0
0
% R
% Ser:
0
7
14
0
0
0
7
7
7
0
7
0
0
14
20
% S
% Thr:
0
0
0
0
0
0
80
47
0
0
87
7
0
0
0
% T
% Val:
0
0
0
0
67
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
87
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _