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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIN All Species: 15.15
Human Site: S215 Identified Species: 25.64
UniProt: O60870 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60870 NP_036443.1 393 45374 S215 S K G A C S S S G A T S S K S
Chimpanzee Pan troglodytes XP_507648 347 40383 K171 D D E E K T A K F I E E Q V R
Rhesus Macaque Macaca mulatta XP_001107965 393 45301 S215 S K G A C S S S G A T S S K S
Dog Lupus familis XP_535194 392 45172 S214 L N K G A C S S A A A S S K S
Cat Felis silvestris
Mouse Mus musculus Q8K339 391 44703 G213 N L N K G A G G S A G A T T S
Rat Rattus norvegicus NP_001102999 392 45040 S214 L N K G A G S S A G A T T S K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509520 392 45338 S214 L N K G A S T S S S S T T P K
Chicken Gallus gallus XP_417297 386 44755 S208 F N L N K G A S T S V A A S S
Frog Xenopus laevis NP_001087479 387 44473 K209 K V A F N L N K G A G T S G T
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_492860 404 46382 S228 G V A S A K I S I F D M P K V
Sea Urchin Strong. purpuratus XP_001179647 387 44388 S209 K V T F S F G S S A G M S A G
Poplar Tree Populus trichocarpa XP_002316291 400 45934 S222 G F A L G L K S N N V G K D R
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_564690 411 47269 A233 G G G V K Q V A T G K E R G E
Baker's Yeast Sacchar. cerevisiae P40962 232 27035 T56 L R K I S Q V T A E D A R R Y
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 87.7 98.7 95.4 N.A. 92.3 93.6 N.A. 89.5 83.2 79.1 N.A. N.A. N.A. N.A. 48.2 59.5
Protein Similarity: 100 87.7 98.9 97.4 N.A. 95.9 96.9 N.A. 95.9 89.3 90.5 N.A. N.A. N.A. N.A. 67.5 73.7
P-Site Identity: 100 0 100 46.6 N.A. 13.3 13.3 N.A. 13.3 13.3 20 N.A. N.A. N.A. N.A. 13.3 20
P-Site Similarity: 100 13.3 100 46.6 N.A. 40 26.6 N.A. 46.6 40 40 N.A. N.A. N.A. N.A. 20 20
Percent
Protein Identity: 48.5 N.A. N.A. 48.6 24.4 N.A.
Protein Similarity: 66 N.A. N.A. 65.2 40.7 N.A.
P-Site Identity: 6.6 N.A. N.A. 6.6 0 N.A.
P-Site Similarity: 6.6 N.A. N.A. 13.3 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 22 15 29 8 15 8 22 43 15 22 8 8 0 % A
% Cys: 0 0 0 0 15 8 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 8 0 0 0 0 0 0 0 0 15 0 0 8 0 % D
% Glu: 0 0 8 8 0 0 0 0 0 8 8 15 0 0 8 % E
% Phe: 8 8 0 15 0 8 0 0 8 8 0 0 0 0 0 % F
% Gly: 22 8 22 22 15 15 15 8 22 15 22 8 0 15 8 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 8 0 0 8 0 8 8 0 0 0 0 0 % I
% Lys: 15 15 29 8 22 8 8 15 0 0 8 0 8 29 15 % K
% Leu: 29 8 8 8 0 15 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 15 0 0 0 % M
% Asn: 8 29 8 8 8 0 8 0 8 8 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 8 8 0 % P
% Gln: 0 0 0 0 0 15 0 0 0 0 0 0 8 0 0 % Q
% Arg: 0 8 0 0 0 0 0 0 0 0 0 0 15 8 15 % R
% Ser: 15 0 0 8 15 22 29 65 22 15 8 22 36 15 36 % S
% Thr: 0 0 8 0 0 8 8 8 15 0 15 22 22 8 8 % T
% Val: 0 22 0 8 0 0 15 0 0 0 15 0 0 8 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _