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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIN
All Species:
15.15
Human Site:
S222
Identified Species:
25.64
UniProt:
O60870
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60870
NP_036443.1
393
45374
S222
S
G
A
T
S
S
K
S
S
T
L
G
P
S
A
Chimpanzee
Pan troglodytes
XP_507648
347
40383
R178
K
F
I
E
E
Q
V
R
R
G
L
E
G
K
E
Rhesus Macaque
Macaca mulatta
XP_001107965
393
45301
S222
S
G
A
T
S
S
K
S
S
T
L
G
P
S
A
Dog
Lupus familis
XP_535194
392
45172
S221
S
A
A
A
S
S
K
S
S
S
L
G
P
S
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8K339
391
44703
S220
G
S
A
G
A
T
T
S
K
S
S
S
L
G
P
Rat
Rattus norvegicus
NP_001102999
392
45040
K221
S
A
G
A
T
T
S
K
S
S
S
L
G
P
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509520
392
45338
K221
S
S
S
S
T
T
P
K
P
S
S
L
G
P
S
Chicken
Gallus gallus
XP_417297
386
44755
S215
S
T
S
V
A
A
S
S
K
T
S
S
I
L
G
Frog
Xenopus laevis
NP_001087479
387
44473
T216
K
G
A
G
T
S
G
T
T
A
S
S
S
H
A
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_492860
404
46382
V235
S
I
F
D
M
P
K
V
K
K
E
D
P
D
E
Sea Urchin
Strong. purpuratus
XP_001179647
387
44388
G216
S
S
A
G
M
S
A
G
G
S
K
E
S
D
S
Poplar Tree
Populus trichocarpa
XP_002316291
400
45934
R229
S
N
N
V
G
K
D
R
G
E
S
S
S
S
R
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_564690
411
47269
E240
A
T
G
K
E
R
G
E
S
S
K
L
L
F
G
Baker's Yeast
Sacchar. cerevisiae
P40962
232
27035
Y63
T
A
E
D
A
R
R
Y
N
I
Q
F
E
K
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.7
98.7
95.4
N.A.
92.3
93.6
N.A.
89.5
83.2
79.1
N.A.
N.A.
N.A.
N.A.
48.2
59.5
Protein Similarity:
100
87.7
98.9
97.4
N.A.
95.9
96.9
N.A.
95.9
89.3
90.5
N.A.
N.A.
N.A.
N.A.
67.5
73.7
P-Site Identity:
100
6.6
100
80
N.A.
13.3
13.3
N.A.
6.6
20
26.6
N.A.
N.A.
N.A.
N.A.
20
20
P-Site Similarity:
100
6.6
100
86.6
N.A.
33.3
40
N.A.
46.6
40
46.6
N.A.
N.A.
N.A.
N.A.
20
33.3
Percent
Protein Identity:
48.5
N.A.
N.A.
48.6
24.4
N.A.
Protein Similarity:
66
N.A.
N.A.
65.2
40.7
N.A.
P-Site Identity:
13.3
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
20
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
22
43
15
22
8
8
0
0
8
0
0
0
0
29
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
15
0
0
8
0
0
0
0
8
0
15
0
% D
% Glu:
0
0
8
8
15
0
0
8
0
8
8
15
8
0
15
% E
% Phe:
0
8
8
0
0
0
0
0
0
0
0
8
0
8
0
% F
% Gly:
8
22
15
22
8
0
15
8
15
8
0
22
22
8
22
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
8
8
0
0
0
0
0
0
8
0
0
8
0
0
% I
% Lys:
15
0
0
8
0
8
29
15
22
8
15
0
0
15
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
29
22
15
8
0
% L
% Met:
0
0
0
0
15
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
8
0
0
0
0
0
8
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
8
8
0
8
0
0
0
29
15
8
% P
% Gln:
0
0
0
0
0
8
0
0
0
0
8
0
0
0
0
% Q
% Arg:
0
0
0
0
0
15
8
15
8
0
0
0
0
0
8
% R
% Ser:
65
22
15
8
22
36
15
36
36
43
43
29
22
29
22
% S
% Thr:
8
15
0
15
22
22
8
8
8
22
0
0
0
0
0
% T
% Val:
0
0
0
15
0
0
8
8
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _