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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIN All Species: 12.73
Human Site: S223 Identified Species: 21.54
UniProt: O60870 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.31
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60870 NP_036443.1 393 45374 S223 G A T S S K S S T L G P S A L
Chimpanzee Pan troglodytes XP_507648 347 40383 R179 F I E E Q V R R G L E G K E Q
Rhesus Macaque Macaca mulatta XP_001107965 393 45301 S223 G A T S S K S S T L G P S A L
Dog Lupus familis XP_535194 392 45172 S222 A A A S S K S S S L G P S A L
Cat Felis silvestris
Mouse Mus musculus Q8K339 391 44703 K221 S A G A T T S K S S S L G P S
Rat Rattus norvegicus NP_001102999 392 45040 S222 A G A T T S K S S S L G P S A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509520 392 45338 P222 S S S T T P K P S S L G P S A
Chicken Gallus gallus XP_417297 386 44755 K216 T S V A A S S K T S S I L G P
Frog Xenopus laevis NP_001087479 387 44473 T217 G A G T S G T T A S S S H A S
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_492860 404 46382 K236 I F D M P K V K K E D P D E P
Sea Urchin Strong. purpuratus XP_001179647 387 44388 G217 S A G M S A G G S K E S D S K
Poplar Tree Populus trichocarpa XP_002316291 400 45934 G230 N N V G K D R G E S S S S R L
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_564690 411 47269 S241 T G K E R G E S S K L L F G D
Baker's Yeast Sacchar. cerevisiae P40962 232 27035 N64 A E D A R R Y N I Q F E K G F
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 87.7 98.7 95.4 N.A. 92.3 93.6 N.A. 89.5 83.2 79.1 N.A. N.A. N.A. N.A. 48.2 59.5
Protein Similarity: 100 87.7 98.9 97.4 N.A. 95.9 96.9 N.A. 95.9 89.3 90.5 N.A. N.A. N.A. N.A. 67.5 73.7
P-Site Identity: 100 6.6 100 80 N.A. 13.3 6.6 N.A. 0 13.3 26.6 N.A. N.A. N.A. N.A. 13.3 13.3
P-Site Similarity: 100 6.6 100 86.6 N.A. 33.3 33.3 N.A. 40 33.3 46.6 N.A. N.A. N.A. N.A. 13.3 26.6
Percent
Protein Identity: 48.5 N.A. N.A. 48.6 24.4 N.A.
Protein Similarity: 66 N.A. N.A. 65.2 40.7 N.A.
P-Site Identity: 13.3 N.A. N.A. 6.6 0 N.A.
P-Site Similarity: 13.3 N.A. N.A. 13.3 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 22 43 15 22 8 8 0 0 8 0 0 0 0 29 15 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 15 0 0 8 0 0 0 0 8 0 15 0 8 % D
% Glu: 0 8 8 15 0 0 8 0 8 8 15 8 0 15 0 % E
% Phe: 8 8 0 0 0 0 0 0 0 0 8 0 8 0 8 % F
% Gly: 22 15 22 8 0 15 8 15 8 0 22 22 8 22 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % H
% Ile: 8 8 0 0 0 0 0 0 8 0 0 8 0 0 0 % I
% Lys: 0 0 8 0 8 29 15 22 8 15 0 0 15 0 8 % K
% Leu: 0 0 0 0 0 0 0 0 0 29 22 15 8 0 29 % L
% Met: 0 0 0 15 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 8 0 0 0 0 0 8 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 8 8 0 8 0 0 0 29 15 8 15 % P
% Gln: 0 0 0 0 8 0 0 0 0 8 0 0 0 0 8 % Q
% Arg: 0 0 0 0 15 8 15 8 0 0 0 0 0 8 0 % R
% Ser: 22 15 8 22 36 15 36 36 43 43 29 22 29 22 15 % S
% Thr: 15 0 15 22 22 8 8 8 22 0 0 0 0 0 0 % T
% Val: 0 0 15 0 0 8 8 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _