KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIN
All Species:
9.09
Human Site:
S228
Identified Species:
15.38
UniProt:
O60870
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60870
NP_036443.1
393
45374
S228
K
S
S
T
L
G
P
S
A
L
K
T
I
G
S
Chimpanzee
Pan troglodytes
XP_507648
347
40383
K184
V
R
R
G
L
E
G
K
E
Q
E
V
P
T
F
Rhesus Macaque
Macaca mulatta
XP_001107965
393
45301
S228
K
S
S
T
L
G
P
S
A
L
K
T
I
G
S
Dog
Lupus familis
XP_535194
392
45172
S227
K
S
S
S
L
G
P
S
A
L
N
A
I
G
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8K339
391
44703
G226
T
S
K
S
S
S
L
G
P
S
A
L
K
L
L
Rat
Rattus norvegicus
NP_001102999
392
45040
P227
S
K
S
S
S
L
G
P
S
A
L
K
M
L
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509520
392
45338
P227
P
K
P
S
S
L
G
P
S
A
L
K
M
V
K
Chicken
Gallus gallus
XP_417297
386
44755
L221
S
S
K
T
S
S
I
L
G
P
S
A
L
K
M
Frog
Xenopus laevis
NP_001087479
387
44473
H222
G
T
T
A
S
S
S
H
A
S
N
A
L
K
S
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_492860
404
46382
D241
K
V
K
K
E
D
P
D
E
P
G
P
S
Q
P
Sea Urchin
Strong. purpuratus
XP_001179647
387
44388
D222
A
G
G
S
K
E
S
D
S
K
A
S
P
N
I
Poplar Tree
Populus trichocarpa
XP_002316291
400
45934
S235
D
R
G
E
S
S
S
S
R
L
V
F
E
E
V
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_564690
411
47269
F246
G
E
S
S
K
L
L
F
G
D
E
E
N
D
K
Baker's Yeast
Sacchar. cerevisiae
P40962
232
27035
K69
R
Y
N
I
Q
F
E
K
G
F
L
Q
L
L
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.7
98.7
95.4
N.A.
92.3
93.6
N.A.
89.5
83.2
79.1
N.A.
N.A.
N.A.
N.A.
48.2
59.5
Protein Similarity:
100
87.7
98.9
97.4
N.A.
95.9
96.9
N.A.
95.9
89.3
90.5
N.A.
N.A.
N.A.
N.A.
67.5
73.7
P-Site Identity:
100
6.6
100
73.3
N.A.
6.6
6.6
N.A.
0
13.3
13.3
N.A.
N.A.
N.A.
N.A.
13.3
0
P-Site Similarity:
100
13.3
100
86.6
N.A.
13.3
26.6
N.A.
20
20
33.3
N.A.
N.A.
N.A.
N.A.
13.3
20
Percent
Protein Identity:
48.5
N.A.
N.A.
48.6
24.4
N.A.
Protein Similarity:
66
N.A.
N.A.
65.2
40.7
N.A.
P-Site Identity:
13.3
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
20
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
0
0
0
0
29
15
15
22
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
8
0
15
0
8
0
0
0
8
0
% D
% Glu:
0
8
0
8
8
15
8
0
15
0
15
8
8
8
0
% E
% Phe:
0
0
0
0
0
8
0
8
0
8
0
8
0
0
8
% F
% Gly:
15
8
15
8
0
22
22
8
22
0
8
0
0
22
8
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
8
0
0
0
0
0
22
0
8
% I
% Lys:
29
15
22
8
15
0
0
15
0
8
15
15
8
15
22
% K
% Leu:
0
0
0
0
29
22
15
8
0
29
22
8
22
22
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
15
0
8
% M
% Asn:
0
0
8
0
0
0
0
0
0
0
15
0
8
8
8
% N
% Pro:
8
0
8
0
0
0
29
15
8
15
0
8
15
0
8
% P
% Gln:
0
0
0
0
8
0
0
0
0
8
0
8
0
8
0
% Q
% Arg:
8
15
8
0
0
0
0
0
8
0
0
0
0
0
0
% R
% Ser:
15
36
36
43
43
29
22
29
22
15
8
8
8
0
22
% S
% Thr:
8
8
8
22
0
0
0
0
0
0
0
15
0
8
0
% T
% Val:
8
8
0
0
0
0
0
0
0
0
8
8
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _