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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DIAPH2
All Species:
26.06
Human Site:
S162
Identified Species:
47.78
UniProt:
O60879
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60879
NP_006720.1
1101
125569
S162
S
K
H
E
C
T
L
S
S
Q
E
Y
V
H
E
Chimpanzee
Pan troglodytes
XP_509808
1253
142880
S236
L
K
R
S
R
Q
I
S
P
Q
E
F
I
H
E
Rhesus Macaque
Macaca mulatta
XP_001087983
1101
125595
S162
S
K
H
E
C
T
L
S
S
Q
E
Y
V
H
E
Dog
Lupus familis
XP_857344
981
113022
L151
E
E
R
S
L
S
L
L
A
K
A
I
D
P
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z207
1171
133668
S154
L
R
S
S
R
Q
I
S
P
Q
E
F
L
H
E
Rat
Rattus norvegicus
XP_001066898
1064
121036
S164
N
K
H
E
F
T
L
S
S
Q
E
Y
V
H
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512687
1111
126766
S184
S
K
H
E
C
T
L
S
S
Q
E
Y
V
H
E
Chicken
Gallus gallus
XP_417020
1172
133968
S147
L
K
N
S
R
K
I
S
P
Q
E
F
I
Q
E
Frog
Xenopus laevis
Q6NTV6
1099
121463
H167
L
C
L
D
A
L
E
H
Y
K
V
V
K
N
Q
Zebra Danio
Brachydanio rerio
XP_683813
932
105075
S147
S
K
H
E
C
T
L
S
S
Q
E
Y
V
H
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P48608
1091
123153
R146
Y
Q
C
V
E
S
L
R
V
A
L
T
S
N
P
Honey Bee
Apis mellifera
XP_395654
1140
128906
N147
L
R
I
A
L
T
N
N
P
L
S
W
V
Q
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_800685
1168
130533
G219
N
D
S
Q
M
K
P
G
D
Y
V
V
E
L
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
52.2
98.4
53
N.A.
53.2
82.1
N.A.
79.2
54.8
21.4
60.6
N.A.
40.8
41.6
N.A.
34.4
Protein Similarity:
100
68.2
99.5
70.5
N.A.
71.2
88.2
N.A.
87.6
71.6
41.2
72.1
N.A.
61
61.4
N.A.
53
P-Site Identity:
100
40
100
13.3
N.A.
33.3
86.6
N.A.
100
33.3
0
100
N.A.
6.6
20
N.A.
0
P-Site Similarity:
100
60
100
40
N.A.
60
93.3
N.A.
100
60
26.6
100
N.A.
26.6
40
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
8
0
0
0
8
8
8
0
0
0
0
% A
% Cys:
0
8
8
0
31
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
8
0
0
0
0
8
0
0
0
8
0
0
% D
% Glu:
8
8
0
39
8
0
8
0
0
0
62
0
8
0
77
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
0
24
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% G
% His:
0
0
39
0
0
0
0
8
0
0
0
0
0
54
8
% H
% Ile:
0
0
8
0
0
0
24
0
0
0
0
8
16
0
0
% I
% Lys:
0
54
0
0
0
16
0
0
0
16
0
0
8
0
0
% K
% Leu:
39
0
8
0
16
8
54
8
0
8
8
0
8
8
0
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
16
0
8
0
0
0
8
8
0
0
0
0
0
16
0
% N
% Pro:
0
0
0
0
0
0
8
0
31
0
0
0
0
8
8
% P
% Gln:
0
8
0
8
0
16
0
0
0
62
0
0
0
16
8
% Q
% Arg:
0
16
16
0
24
0
0
8
0
0
0
0
0
0
0
% R
% Ser:
31
0
16
31
0
16
0
62
39
0
8
0
8
0
0
% S
% Thr:
0
0
0
0
0
47
0
0
0
0
0
8
0
0
0
% T
% Val:
0
0
0
8
0
0
0
0
8
0
16
16
47
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
8
8
0
39
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _