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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DIAPH2
All Species:
5.15
Human Site:
S27
Identified Species:
9.44
UniProt:
O60879
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60879
NP_006720.1
1101
125569
S27
G
G
R
S
N
K
R
S
A
G
N
R
A
A
N
Chimpanzee
Pan troglodytes
XP_509808
1253
142880
H104
P
R
R
K
G
P
Q
H
P
P
P
P
S
G
P
Rhesus Macaque
Macaca mulatta
XP_001087983
1101
125595
S27
G
G
R
S
N
K
R
S
A
G
N
R
A
A
N
Dog
Lupus familis
XP_857344
981
113022
A30
V
M
Q
Y
I
N
T
A
S
K
T
V
T
A
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z207
1171
133668
A27
G
L
Q
S
A
P
P
A
G
P
Y
E
P
G
E
Rat
Rattus norvegicus
XP_001066898
1064
121036
G29
V
G
R
S
N
K
R
G
T
G
N
R
A
A
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512687
1111
126766
L49
G
A
G
F
W
G
V
L
S
R
E
L
R
T
S
Chicken
Gallus gallus
XP_417020
1172
133968
P28
G
L
R
R
K
G
P
P
A
A
G
G
P
E
E
Frog
Xenopus laevis
Q6NTV6
1099
121463
E27
P
Q
D
P
D
Q
I
E
G
N
L
E
N
A
D
Zebra Danio
Brachydanio rerio
XP_683813
932
105075
K28
E
D
E
S
K
N
K
K
L
N
I
H
I
K
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P48608
1091
123153
G27
G
R
P
S
K
S
K
G
G
T
I
S
S
G
T
Honey Bee
Apis mellifera
XP_395654
1140
128906
G26
R
P
K
K
S
G
R
G
G
G
V
R
S
G
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_800685
1168
130533
S61
S
G
T
P
T
M
D
S
G
T
P
T
M
D
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
52.2
98.4
53
N.A.
53.2
82.1
N.A.
79.2
54.8
21.4
60.6
N.A.
40.8
41.6
N.A.
34.4
Protein Similarity:
100
68.2
99.5
70.5
N.A.
71.2
88.2
N.A.
87.6
71.6
41.2
72.1
N.A.
61
61.4
N.A.
53
P-Site Identity:
100
6.6
100
6.6
N.A.
13.3
80
N.A.
6.6
20
6.6
6.6
N.A.
13.3
20
N.A.
13.3
P-Site Similarity:
100
20
100
33.3
N.A.
26.6
80
N.A.
20
20
26.6
13.3
N.A.
26.6
40
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
8
0
0
16
24
8
0
0
24
39
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
8
0
8
0
8
0
0
0
0
0
0
8
8
% D
% Glu:
8
0
8
0
0
0
0
8
0
0
8
16
0
8
16
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
47
31
8
0
8
24
0
24
39
31
8
8
0
31
0
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
8
0
0
0
% H
% Ile:
0
0
0
0
8
0
8
0
0
0
16
0
8
0
0
% I
% Lys:
0
0
8
16
24
24
16
8
0
8
0
0
0
8
0
% K
% Leu:
0
16
0
0
0
0
0
8
8
0
8
8
0
0
8
% L
% Met:
0
8
0
0
0
8
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
24
16
0
0
0
16
24
0
8
0
24
% N
% Pro:
16
8
8
16
0
16
16
8
8
16
16
8
16
0
8
% P
% Gln:
0
8
16
0
0
8
8
0
0
0
0
0
0
0
0
% Q
% Arg:
8
16
39
8
0
0
31
0
0
8
0
31
8
0
8
% R
% Ser:
8
0
0
47
8
8
0
24
16
0
0
8
24
0
16
% S
% Thr:
0
0
8
0
8
0
8
0
8
16
8
8
8
8
16
% T
% Val:
16
0
0
0
0
0
8
0
0
0
8
8
0
0
0
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _