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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DIAPH2
All Species:
23.64
Human Site:
S392
Identified Species:
43.33
UniProt:
O60879
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60879
NP_006720.1
1101
125569
S392
E
D
D
L
T
E
L
S
H
R
L
N
D
I
R
Chimpanzee
Pan troglodytes
XP_509808
1253
142880
S465
E
E
D
L
F
E
L
S
H
R
L
E
D
I
R
Rhesus Macaque
Macaca mulatta
XP_001087983
1101
125595
S392
E
D
D
L
T
E
L
S
H
R
L
N
D
I
R
Dog
Lupus familis
XP_857344
981
113022
S330
L
L
I
R
N
D
Y
S
I
R
Q
Q
Y
F
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z207
1171
133668
F383
E
E
D
L
S
E
F
F
H
R
L
E
D
I
R
Rat
Rattus norvegicus
XP_001066898
1064
121036
S394
E
D
D
L
T
E
L
S
H
R
L
N
D
I
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512687
1111
126766
S414
E
D
D
L
T
E
L
S
H
R
L
N
D
I
R
Chicken
Gallus gallus
XP_417020
1172
133968
S376
E
E
D
M
I
E
F
S
H
R
L
E
D
I
R
Frog
Xenopus laevis
Q6NTV6
1099
121463
T419
A
C
I
T
P
L
H
T
H
L
S
G
E
L
T
Zebra Danio
Brachydanio rerio
XP_683813
932
105075
F363
L
D
I
Q
L
K
V
F
N
E
N
K
E
E
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P48608
1091
123153
V359
E
D
D
F
E
E
F
V
Q
R
F
D
N
V
T
Honey Bee
Apis mellifera
XP_395654
1140
128906
V342
E
E
D
Y
E
E
F
V
Q
R
F
D
H
V
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_800685
1168
130533
N466
C
V
C
M
Q
L
V
N
A
I
I
S
N
P
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
52.2
98.4
53
N.A.
53.2
82.1
N.A.
79.2
54.8
21.4
60.6
N.A.
40.8
41.6
N.A.
34.4
Protein Similarity:
100
68.2
99.5
70.5
N.A.
71.2
88.2
N.A.
87.6
71.6
41.2
72.1
N.A.
61
61.4
N.A.
53
P-Site Identity:
100
80
100
13.3
N.A.
66.6
100
N.A.
100
66.6
6.6
6.6
N.A.
33.3
33.3
N.A.
0
P-Site Similarity:
100
86.6
100
26.6
N.A.
80
100
N.A.
100
80
26.6
33.3
N.A.
53.3
53.3
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% A
% Cys:
8
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
47
70
0
0
8
0
0
0
0
0
16
54
0
8
% D
% Glu:
70
31
0
0
16
70
0
0
0
8
0
24
16
8
8
% E
% Phe:
0
0
0
8
8
0
31
16
0
0
16
0
0
8
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% G
% His:
0
0
0
0
0
0
8
0
62
0
0
0
8
0
0
% H
% Ile:
0
0
24
0
8
0
0
0
8
8
8
0
0
54
0
% I
% Lys:
0
0
0
0
0
8
0
0
0
0
0
8
0
0
8
% K
% Leu:
16
8
0
47
8
16
39
0
0
8
54
0
0
8
0
% L
% Met:
0
0
0
16
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
0
8
8
0
8
31
16
0
0
% N
% Pro:
0
0
0
0
8
0
0
0
0
0
0
0
0
8
0
% P
% Gln:
0
0
0
8
8
0
0
0
16
0
8
8
0
0
0
% Q
% Arg:
0
0
0
8
0
0
0
0
0
77
0
0
0
0
62
% R
% Ser:
0
0
0
0
8
0
0
54
0
0
8
8
0
0
0
% S
% Thr:
0
0
0
8
31
0
0
8
0
0
0
0
0
0
16
% T
% Val:
0
8
0
0
0
0
16
16
0
0
0
0
0
16
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
8
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _