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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DIAPH2 All Species: 11.21
Human Site: S544 Identified Species: 20.56
UniProt: O60879 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60879 NP_006720.1 1101 125569 S544 T Q A Q V L S S S S G I P G P
Chimpanzee Pan troglodytes XP_509808 1253 142880 D617 S Q V K F H S D C H A P V T A
Rhesus Macaque Macaca mulatta XP_001087983 1101 125595 S544 T Q A Q V L S S S S G I P G P
Dog Lupus familis XP_857344 981 113022 M472 P P L P G M P M P F G G P V P
Cat Felis silvestris
Mouse Mus musculus Q9Z207 1171 133668 P535 S Q F G A L P P G T K I P L Q
Rat Rattus norvegicus XP_001066898 1064 121036 F546 A Q G P G S A F P G P P P P P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512687 1111 126766 T566 T Q G P G L S T S S G V S P P
Chicken Gallus gallus XP_417020 1172 133968 S560 P P P P P L P S N G A I P P P
Frog Xenopus laevis Q6NTV6 1099 121463 G486 P P P P P L P G M G G M L P P
Zebra Danio Brachydanio rerio XP_683813 932 105075 L501 R Q E A Q A E L Q K Q E E K I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P48608 1091 123153 V509 S P N K L P K V N I P M P P P
Honey Bee Apis mellifera XP_395654 1140 128906 N486 Q G G I K S T N G N K I G S V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_800685 1168 130533 S621 E L K Q R V A S G A V V A A T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 52.2 98.4 53 N.A. 53.2 82.1 N.A. 79.2 54.8 21.4 60.6 N.A. 40.8 41.6 N.A. 34.4
Protein Similarity: 100 68.2 99.5 70.5 N.A. 71.2 88.2 N.A. 87.6 71.6 41.2 72.1 N.A. 61 61.4 N.A. 53
P-Site Identity: 100 13.3 100 20 N.A. 26.6 20 N.A. 53.3 33.3 20 6.6 N.A. 13.3 6.6 N.A. 13.3
P-Site Similarity: 100 26.6 100 26.6 N.A. 40 26.6 N.A. 66.6 40 26.6 6.6 N.A. 46.6 26.6 N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 16 8 8 8 16 0 0 8 16 0 8 8 8 % A
% Cys: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % D
% Glu: 8 0 8 0 0 0 8 0 0 0 0 8 8 0 0 % E
% Phe: 0 0 8 0 8 0 0 8 0 8 0 0 0 0 0 % F
% Gly: 0 8 24 8 24 0 0 8 24 24 39 8 8 16 0 % G
% His: 0 0 0 0 0 8 0 0 0 8 0 0 0 0 0 % H
% Ile: 0 0 0 8 0 0 0 0 0 8 0 39 0 0 8 % I
% Lys: 0 0 8 16 8 0 8 0 0 8 16 0 0 8 0 % K
% Leu: 0 8 8 0 8 47 0 8 0 0 0 0 8 8 0 % L
% Met: 0 0 0 0 0 8 0 8 8 0 0 16 0 0 0 % M
% Asn: 0 0 8 0 0 0 0 8 16 8 0 0 0 0 0 % N
% Pro: 24 31 16 39 16 8 31 8 16 0 16 16 54 39 62 % P
% Gln: 8 54 0 24 8 0 0 0 8 0 8 0 0 0 8 % Q
% Arg: 8 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 24 0 0 0 0 16 31 31 24 24 0 0 8 8 0 % S
% Thr: 24 0 0 0 0 0 8 8 0 8 0 0 0 8 8 % T
% Val: 0 0 8 0 16 8 0 8 0 0 8 16 8 8 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _