KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DIAPH2
All Species:
16.36
Human Site:
S61
Identified Species:
30
UniProt:
O60879
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60879
NP_006720.1
1101
125569
S61
D
V
R
D
R
I
T
S
F
R
K
S
T
V
K
Chimpanzee
Pan troglodytes
XP_509808
1253
142880
S138
D
M
L
D
K
F
A
S
I
R
I
P
G
S
K
Rhesus Macaque
Macaca mulatta
XP_001087983
1101
125595
S61
D
V
R
D
R
I
T
S
F
R
K
S
T
V
K
Dog
Lupus familis
XP_857344
981
113022
G64
F
I
H
E
L
K
M
G
S
A
D
E
R
L
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z207
1171
133668
G61
F
A
S
I
R
I
P
G
S
K
K
E
R
P
P
Rat
Rattus norvegicus
XP_001066898
1064
121036
S63
D
V
R
D
R
I
T
S
F
R
K
S
A
I
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512687
1111
126766
S83
D
M
R
D
R
I
T
S
F
R
K
S
A
V
K
Chicken
Gallus gallus
XP_417020
1172
133968
A62
G
S
K
K
E
R
P
A
L
P
H
M
K
Q
S
Frog
Xenopus laevis
Q6NTV6
1099
121463
D61
K
K
R
L
E
S
S
D
D
E
W
M
C
Q
F
Zebra Danio
Brachydanio rerio
XP_683813
932
105075
P62
E
K
P
L
I
Q
H
P
T
D
P
I
S
T
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P48608
1091
123153
Q61
D
F
E
Q
Y
I
Q
Q
L
S
V
A
E
L
D
Honey Bee
Apis mellifera
XP_395654
1140
128906
M60
Q
R
C
I
I
E
R
M
D
K
E
N
S
N
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_800685
1168
130533
S95
K
K
R
K
E
N
G
S
V
T
D
D
S
I
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
52.2
98.4
53
N.A.
53.2
82.1
N.A.
79.2
54.8
21.4
60.6
N.A.
40.8
41.6
N.A.
34.4
Protein Similarity:
100
68.2
99.5
70.5
N.A.
71.2
88.2
N.A.
87.6
71.6
41.2
72.1
N.A.
61
61.4
N.A.
53
P-Site Identity:
100
33.3
100
0
N.A.
20
86.6
N.A.
86.6
0
6.6
0
N.A.
13.3
0
N.A.
13.3
P-Site Similarity:
100
46.6
100
20
N.A.
26.6
93.3
N.A.
93.3
13.3
13.3
20
N.A.
26.6
26.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
8
8
0
8
0
8
16
0
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
47
0
0
39
0
0
0
8
16
8
16
8
0
0
16
% D
% Glu:
8
0
8
8
24
8
0
0
0
8
8
16
8
0
0
% E
% Phe:
16
8
0
0
0
8
0
0
31
0
0
0
0
0
8
% F
% Gly:
8
0
0
0
0
0
8
16
0
0
0
0
8
0
0
% G
% His:
0
0
8
0
0
0
8
0
0
0
8
0
0
0
0
% H
% Ile:
0
8
0
16
16
47
0
0
8
0
8
8
0
16
0
% I
% Lys:
16
24
8
16
8
8
0
0
0
16
39
0
8
0
39
% K
% Leu:
0
0
8
16
8
0
0
0
16
0
0
0
0
16
8
% L
% Met:
0
16
0
0
0
0
8
8
0
0
0
16
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
0
0
0
8
0
8
0
% N
% Pro:
0
0
8
0
0
0
16
8
0
8
8
8
0
8
8
% P
% Gln:
8
0
0
8
0
8
8
8
0
0
0
0
0
16
8
% Q
% Arg:
0
8
47
0
39
8
8
0
0
39
0
0
16
0
0
% R
% Ser:
0
8
8
0
0
8
8
47
16
8
0
31
24
8
8
% S
% Thr:
0
0
0
0
0
0
31
0
8
8
0
0
16
8
0
% T
% Val:
0
24
0
0
0
0
0
0
8
0
8
0
0
24
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _